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  2. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    Acute use (1–3 days) yields a potency about 1.5× stronger than that of morphine and chronic use (7 days+) yields a potency about 2.5 to 5× that of morphine. Similarly, the effect of tramadol increases after consecutive dosing due to the accumulation of its active metabolite and an increase of the oral bioavailability in chronic use.

  3. Potency (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Potency_(pharmacology)

    In pharmacology, potency or biological potency [1] is a measure of a drug's biological activity expressed in terms of the dose required to produce a pharmacological effect of given intensity. [2]

  4. Dose–response relationship - Wikipedia

    en.wikipedia.org/wiki/Dose–response_relationship

    The parameters of the dose response curve reflect measures of potency (such as EC50, IC50, ED50, etc.) and measures of efficacy (such as tissue, cell or population response). A commonly used dose–response curve is the EC 50 curve, the half maximal effective concentration, where the EC 50 point is defined as the inflection point of the curve.

  5. NYT ‘Connections’ Hints and Answers Today, Thursday, February 13

    www.aol.com/nyt-connections-hints-answers-today...

    2. Different ways to show feelings of gratitude. 3. Auxillary words that indicate "possibility" or "necessity." 4. The words in this category precede a four-letter noun (hint: the noun typically ...

  6. Area under the curve (pharmacokinetics) - Wikipedia

    en.wikipedia.org/wiki/Area_under_the_curve...

    AUC is a useful metric when trying to determine whether two formulations of the same dose (for example a capsule and a tablet) result in equal amounts of tissue or plasma exposure. Another use is in the therapeutic drug monitoring of drugs with a narrow therapeutic index.

  7. IC50 - Wikipedia

    en.wikipedia.org/wiki/IC50

    Half maximal inhibitory concentration (IC 50) is a measure of the potency of a substance in inhibiting a specific biological or biochemical function. IC 50 is a quantitative measure that indicates how much of a particular inhibitory substance (e.g. drug) is needed to inhibit, in vitro , a given biological process or biological component by 50% ...

  8. Kosher Salt vs. Table Salt: An Expert Explains the Difference

    www.aol.com/kosher-salt-vs-table-salt-140100679.html

    If you are using Morton Kosher Salt, I recommend using about 1 1/2 teaspoons of Morton Kosher for each teaspoon of table salt called for in the recipe. The Takeaway.

  9. Eric Dickerson isn't rooting for Saquon Barkley to break his ...

    www.aol.com/sports/eric-dickerson-isnt-rooting...

    With 1,838 yards, the seven-year veteran has to average 133.5 yards in those final two games to seize the all-time mark. Barkley has topped that number in six of his 15 games this season.