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  2. Metformin - Wikipedia

    en.wikipedia.org/wiki/Metformin

    The US Food and Drug Administration (FDA) recommends avoiding the use of metformin in more severe chronic kidney disease, below the eGFR cutoff of 30 mL/minute/1.73 m 2. [94] Lactate uptake by the liver is diminished with metformin use because lactate is a substrate for hepatic gluconeogenesis, a process that metformin inhibits.

  3. 6 Potential Long-Term Effects of Ozempic - AOL

    www.aol.com/6-potential-long-term-effects...

    Some severe side effects with long-term consequences may include pancreatitis, acute kidney injury, gallstones, gallbladder disease, diabetic retinopathy, and an increased heart rate. Semaglutide ...

  4. Diabetes medication - Wikipedia

    en.wikipedia.org/wiki/Diabetes_medication

    Although it must be used with caution in patients with impaired liver or kidney function, Metformin, a biguanide, has become the most commonly used agent for type 2 diabetes in children and teenagers. Among common diabetic drugs, Metformin is the only widely used oral drug that does not cause weight gain. [9]

  5. GLP-1 receptor agonist - Wikipedia

    en.wikipedia.org/wiki/GLP-1_receptor_agonist

    They are also a first-line treatment for people with both type 2 diabetes and kidney disease. Both types of medication can be combined with metformin. [8] [9] One advantage of GLP-1 agonists over older insulin secretagogues, such as sulfonylureas or meglitinides, is that they have a lower risk of causing hypoglycemia. [10]

  6. When Is the Best Time to Take Metformin? - AOL

    www.aol.com/best-time-metformin-141700387.html

    Well, there’s no magic time, but you should take metformin at the same time each day and with food to avoid gastrointestinal side effects. If you’re taking extended-release metformin tablets ...

  7. Erythropoiesis-stimulating agent - Wikipedia

    en.wikipedia.org/wiki/Erythropoiesis-stimulating...

    Erythropoiesis-stimulating agents (ESA) are medications which stimulate the bone marrow to make red blood cells. [1] They are used to treat anemia due to end stage kidney disease, chemotherapy, major surgery, or certain treatments in HIV/AIDS. [1] [2] In these situations they decrease the need for blood transfusions. [2]

  8. Why do some researchers believe metformin may hold the key to ...

    www.aol.com/lifestyle/why-researchers-believe...

    Some researchers are investigating how metformin, a common drug used to treat diabetes, may help prolong healthspan and lifespan. What evidence is there to support this notion?

  9. Nephrotoxicity - Wikipedia

    en.wikipedia.org/wiki/Nephrotoxicity

    Nephrotoxicity is toxicity in the kidneys.It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. [1] There are various forms, [2] and some drugs may affect kidney function in more than one way.

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