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Myostatin inhibitors are a class of drugs that work by blocking the effect of myostatin, which inhibits muscle growth. In animal models and limited human studies, myostatin inhibitors have increased muscle size. They are being developed to treat obesity, sarcopenia, muscular dystrophy, and other illnesses.
Generally, drugs outlined within the ATC code M should be included in this category. Please see WP:PHARM:CAT for more information. Wikimedia Commons has media related to Musculoskeletal drugs .
4 Ways to Prevent Muscle Loss on Ozempic & Other Weight Loss GLP-1 Medications. You can’t go far lately without seeing news and social media coverage of GLP-1 (glucagon-like peptide-1) receptor ...
geographic atrophy secondary to age-related macular degeneration Lanadelumab [41] Takhzyro: mab: human: kallikrein: Y: angioedema: Landogrozumab [12] mab: humanized: GDF-8: muscle wasting disorders Laprituximab emtansine [41] mab: chimeric: epidermal growth factor receptor (EGFR) Larcaviximab [28] mab: chimeric: ebolavirus glycoprotein: Ebola ...
ATC code M01 Anti-inflammatory and antirheumatic products is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
There are currently no approved medications for the treatment of sarcopenia. [41] Testosterone or other anabolic steroids have also been investigated for treatment of sarcopenia, and seem to have some positive effects on muscle strength and mass, but cause several side effects and raise concerns of prostate cancer in men and virilization in women.
Muscle atrophy is the loss of skeletal muscle mass. It can be caused by immobility, aging, malnutrition, medications, or a wide range of injuries or diseases that impact the musculoskeletal or nervous system. Muscle atrophy leads to muscle weakness and causes disability.
One aspect hindering drug approval for treatments for cachexia and sarcopenia (two types of muscle wasting) is disagreement in what outcomes would demonstrate the efficacy of a drug. Several clinical trials have found that SARMs improve lean mass in humans, but it is not clear whether strength and physical function are also improved.