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  2. Henderson–Hasselbalch equation - Wikipedia

    en.wikipedia.org/wiki/Henderson–Hasselbalch...

    The Henderson–Hasselbalch equation can be used to model these equilibria. It is important to maintain this pH of 7.4 to ensure enzymes are able to work optimally. [10] Life threatening Acidosis (a low blood pH resulting in nausea, headaches, and even coma, and convulsions) is due to a lack of functioning of enzymes at a low pH. [10]

  3. pH - Wikipedia

    en.wikipedia.org/wiki/PH

    When an acid is dissolved in water, the pH will be less than 7, while a base, or alkali, will have a pH greater than 7. A strong acid, such as hydrochloric acid, at concentration 1 mol dm −3 has a pH of 0, while a strong alkali like sodium hydroxide, at the same concentration, has a pH of 14. Since pH is a logarithmic scale, a difference of ...

  4. Weak base - Wikipedia

    en.wikipedia.org/wiki/Weak_base

    With pOH obtained from the pOH formula given above, the pH of the base can then be calculated from =, where pK w = 14.00. A weak base persists in chemical equilibrium in much the same way as a weak acid does, with a base dissociation constant (K b) indicating the strength of the base. For example, when ammonia is put in water, the following ...

  5. Charlot equation - Wikipedia

    en.wikipedia.org/wiki/Charlot_equation

    The Charlot equation, named after Gaston Charlot, is used in analytical chemistry to relate the hydrogen ion concentration, and therefore the pH, with the formal analytical concentration of an acid and its conjugate base. It can be used for computing the pH of buffer solutions when the approximations of the Henderson–Hasselbalch equation ...

  6. Partition coefficient - Wikipedia

    en.wikipedia.org/wiki/Partition_coefficient

    The distribution coefficient, log D, is the ratio of the sum of the concentrations of all forms of the compound (ionized plus un-ionized) in each of the two phases, one essentially always aqueous; as such, it depends on the pH of the aqueous phase, and log D = log P for non-ionizable compounds at any pH. [13] [14] For measurements of ...

  7. Equilibrium constant - Wikipedia

    en.wikipedia.org/wiki/Equilibrium_constant

    where log denotes a logarithm to base 10 or common logarithm, and K diss is a stepwise acid dissociation constant. For bases, the base association constant , p K b is used. For any given acid or base the two constants are related by p K a + p K b = p K w , so p K a can always be used in calculations.

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  9. Acid dissociation constant - Wikipedia

    en.wikipedia.org/wiki/Acid_dissociation_constant

    Likewise, any aqueous base with an association constant pK b less than about 0, corresponding to pK a greater than about 14, is leveled to OH − and is considered a strong base. [ 22 ] Nitric acid , with a p K value of around −1.7, behaves as a strong acid in aqueous solutions with a pH greater than 1. [ 23 ]