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The liver span is a measurement performed during physical examination to determine the size of the liver and identify possible hepatomegaly.. It is the distance between the lower border of the liver in the mid-clavicular line obtained by palpation, and the upper border of the liver in the mid-clavicular line detected by percussion (the upper border of the liver lies behind the ribs and can not ...
Suspicion of hepatomegaly indicates a thorough medical history and physical examination, wherein the latter typically includes an increased liver span. [citation needed] On abdominal ultrasonography, the liver can be measured by the maximum dimension on a sagittal plane view through the midclavicular line, which is normally up to 18 cm in ...
Liver size can be enlarged, normal, or shrunken in people with cirrhosis. [36] As the disease progresses, the liver will typically shrink due to the result of scarring. [37] Jaundice is the yellowing of the skin. It can additionally cause yellowing of mucous membranes notably of the white of the eyes.
About 20,000 protein coding genes are expressed in human cells and 60% of these genes are expressed in a normal, adult liver. [34] [35] Over 400 genes are more specifically expressed in the liver, with some 150 genes highly specific for liver tissue.
The liver scratch test can be used when other exam techniques used to approximate liver size are ineffective or unavailable [2] and is thought to be most useful if the abdomen is distended, too tender for direct palpation, the abdominal muscles are too rigid, or the patient is obese.
The typical hepatocyte is cubical with sides of 20-30 μm, (in comparison, a human hair has a diameter of 17 to 180 μm). [1] The typical volume of a hepatocyte is 3.4 x 10 −9 cm 3 . [ 2 ] Smooth endoplasmic reticulum is abundant in hepatocytes, in contrast to most other cell types.
A liver segment is one of eight segments of the liver as described in the widely used Couinaud classification (named after Claude Couinaud) in the anatomy of the liver.This system divides the lobes of the liver into eight segments based on a transverse plane through the bifurcation of the main portal vein, [1] arranged in a clockwise manner starting from the caudate lobe.
Liver function tests (LFTs or LFs), also referred to as a hepatic panel or liver panel, are groups of blood tests that provide information about the state of a patient's liver. [1] These tests include prothrombin time (PT/INR), activated partial thromboplastin time (aPTT), albumin , bilirubin (direct and indirect), and others.
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