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In pharmacology, potency or biological potency [1] is a measure of a drug's biological activity expressed in terms of the dose required to produce a pharmacological effect of given intensity. [2]
The award was part of a U.S. Navy prototype contract that pre-dated the war; field testing had begun in 2021 and after the system was submitted to the DOD in April 2022, range and durability tests were conducted in the summer. 14 kits would be installed on vehicles the U.S. provided Ukraine, with four systems to be delivered by mid-2023 and 10 ...
Log–log plot comparing the yield (in kilotonnes) and mass (in kilograms) of various nuclear weapons developed by the United States.. The explosive yield of a nuclear weapon is the amount of energy released such as blast, thermal, and nuclear radiation, when that particular nuclear weapon is detonated, usually expressed as a TNT equivalent (the standardized equivalent mass of trinitrotoluene ...
The VP weight is an indicator of the androgenic effect, while the LA weight is an indicator of the anabolic effect. Two or more batches of rats are castrated and given no treatment and respectively some AAS of interest.
A dose-additive response occurs when the mixture effect is determined by the sum of the component chemical doses, each weighted by its relative toxic potency. A risk-additive response occurs when the mixture response is the sum of component risks, based on the probability law of independent events.
˙ is the mass generation rate of the substance - assumed to be a constant, i.e. not a function of time (equal to zero for exogenous (foreign) substances/drugs) [mmol/min] or [mol/s] t is dialysis time or time since injection of the substance/drug [min] or [s] V is the volume of distribution or total body water [L] or [m 3]
The median lethal dose, LD 50 (abbreviation for "lethal dose, 50%"), LC 50 (lethal concentration, 50%) or LCt 50 (lethal concentration and time) of a toxin, radiation, or pathogen is the dose required to kill half the members of a tested population after a specified test duration.
The lack of modern conventional attack capability prompted calls for a specialized attack aircraft. [ 10 ] [ 11 ] On 7 June 1961, the Secretary of Defense Robert McNamara ordered the USAF to develop two tactical aircraft, one for the long-range strike and interdictor role, and the other focusing on the fighter-bomber mission.