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Thyroid hormone leads to heat generation in humans. However, the thyronamines function via some unknown mechanism to inhibit neuronal activity; this plays an important role in the hibernation cycles of mammals and the moulting behaviour of birds. One effect of administering the thyronamines is a severe drop in body temperature.
The human thyroid (tan), as viewed from the front; and arteries (red) supplying the gland. The thyroid gland is a butterfly-shaped gland located in the neck below the Adam's apple. The thyroid, or thyroid gland, is an endocrine gland in vertebrates. In humans, it is in the neck and consists of two connected lobes.
Levothyroxine. Levothyroxine, also known as L-thyroxine, is a synthetic form of the thyroid hormone thyroxine (T 4 ). [ 5][ 8] It is used to treat thyroid hormone deficiency (hypothyroidism), including a severe form known as myxedema coma. [ 5] It may also be used to treat and prevent certain types of thyroid tumors. [ 5]
Antithyroid agent. An antithyroid agent is a hormone inhibitor acting upon thyroid hormones . The main antithyroid drugs are carbimazole (in the UK), methimazole (in the US), and propylthiouracil (PTU). A less common antithyroid agent is potassium perchlorate .
Hypothyroidism (also called underactive thyroid, low thyroid or hypothyreosis) is a disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormones. [3] It can cause a number of symptoms, such as poor ability to tolerate cold , extreme fatigue, muscle aches , constipation , slow heart rate , depression , and ...
Thyroid-stimulating hormone (also known as thyrotropin, thyrotropic hormone, or abbreviated TSH) is a pituitary hormone that stimulates the thyroid gland to produce thyroxine (T 4 ), and then triiodothyronine (T 3) which stimulates the metabolism of almost every tissue in the body. [ 1] It is a glycoprotein hormone produced by thyrotrope cells ...
T 3 is the more metabolically active hormone produced from T 4.T 4 is deiodinated by three deiodinase enzymes to produce the more-active triiodothyronine: . Type I present in liver, kidney, thyroid, and (to a lesser extent) pituitary; it accounts for 80% of the deiodination of T 4.
Liothyronine is the most potent form of thyroid hormone. As a salt of triiodothyronine (T 3 ), it is chemically similar and pharmacologically equivalent to T 3. As such, it acts on the body to increase the basal metabolic rate, affect protein synthesis and increase the body's sensitivity to catecholamines (such as adrenaline) by permissiveness.