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Amitriptyline. Amitriptyline, sold under the brand name Elavil among others, is a tricyclic antidepressant primarily used to treat major depressive disorder, and a variety of pain syndromes such as neuropathic pain, fibromyalgia, migraine and tension headaches. [ 12] Due to the frequency and prominence of side effects, amitriptyline is ...
Nortriptyline, sold under the brand name Aventyl, among others, is a tricyclic antidepressant. This medicine is also sometimes used for neuropathic pain, attention deficit hyperactivity disorder (ADHD), smoking cessation and anxiety. [ 5][ 6] As with many antidepressants, its use for young people with depression and other psychiatric disorders ...
Tricyclic antidepressants ( TCAs) are a class of medications that are used primarily as antidepressants. TCAs were discovered in the early 1950s and were marketed later in the decade. [ 1] They are named after their chemical structure, which contains three rings of atoms. Tetracyclic antidepressants (TeCAs), which contain four rings of atoms ...
Similar to other TCAs, amitriptyline is more likely to cause certain side effects than newer medications. A study by JAMA Psychiatry found that amitriptyline is one of the depression medications ...
Due to its side effects, amitriptyline isn’t commonly used as a first-line treatment for depression. Viorel Kurnosov/istockphoto Another well-known TCA is doxepin, sold under the name Silenor.
Common (>1% incidence) adverse effects include [1] [2] [4]Sedation; Hypertension; Neurological impairments (such as extrapyramidal side effects which include dystonia, akathisia, parkinsonism, muscle rigidity, etc.)
Tricyclic antidepressant overdose is poisoning caused by excessive medication of the tricyclic antidepressant (TCA) type. Symptoms may include elevated body temperature, blurred vision, dilated pupils, sleepiness, confusion, seizures, rapid heart rate, and cardiac arrest. [ 1]
Tianeptine shows efficacy against serious depressive episodes ( major depression ), comparable to amitriptyline, imipramine and fluoxetine, but with significantly fewer side effects. [ 18] It was shown to be more effective than maprotiline in a group of people with co-existing depression and anxiety. [ 10]