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Treatment to protect the airway may include intubation or cricothyroidotomy. [1] Histamine-related angioedema can be treated with antihistamines , corticosteroids , and epinephrine . [ 1 ] In those with bradykinin-related disease a C1 esterase inhibitor , ecallantide , or icatibant may be used. [ 1 ]
Allergen immunotherapy is an alternative treatment considered in some patients, with a success rate of 80%-90% in reducing symptoms, [3] but requiring a much longer duration of therapy. The choice of medications depends on the disease to be treated, its severity and patient factors.
The risk of first-degree relatives developing the same hypersensitivity reaction is higher than in the general population. [1] As this syndrome can present secondary to multiple anticonvulsants, the general term "anticonvulsant hypersensitivity syndrome" (AHS) is favored over the original descriptive term "dilantin hypersensitivity syndrome."
The evidence does not report how antihistamines affect women differently than men. [1] Different studies have reported on antihistamine use in children, with various studies finding evidence that certain antihistamines could be used by children 2 years of age, and other drugs being safer for younger or older children.
Cyproheptadine, sold under the brand name Periactin among others, is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties. It was patented in 1959 and came into medical use in 1961. [ 5 ]
Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. [5] This includes allergic rhinitis (hay fever) and hives. [5] It is also available in drug combinations such as loratadine/pseudoephedrine, in which it is combined with pseudoephedrine, a nasal decongestant. [5]
Anti-reflux medications may be prescribed for patients with signs of chronic laryngitis and hoarse voice. [24] If anti-reflux treatment does not result in a decrease of symptoms, other possible causes should be examined. [1] Over-the-counter medications for neutralizing acids and acid suppressants (H-2 blockers) may be used. [7]
Treatment of VCD often combines behavioral, medical, and psychological approaches, most often including an otolaryngologist, a psychologist, and a speech-language pathologist. [1] Although information on the incidence and prevalence of VCD is limited, it is known to occur most frequently in young women.
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109 S High St #100, Columbus, OH · Directions · (614) 224-4261