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Gamma-glutamyltransferase (also γ-glutamyltransferase, GGT, gamma-GT, gamma-glutamyl transpeptidase; [1] EC 2.3.2.2) is a transferase (a type of enzyme) that catalyzes the transfer of gamma-glutamyl functional groups from molecules such as glutathione to an acceptor that may be an amino acid, a peptide or water (forming glutamate).
Dirlotapide is a drug used to treat obesity in dogs. [1] It is manufactured by Pfizer and Zoetis and marketed under the brand name Slentrol. [citation needed]It works as a gut-selective microsomal triglyceride transfer protein (MTTP or MTP) inhibitor. [2]
nimesulide – nonsteroidal anti-inflammatory drug (NSAID) nitarsone – feed additive used in poultry to increase weight gain, improve feed efficiency, and prevent histomoniasis (blackhead disease) nitenpyram – insecticide; nitroscanate – anthelmintic used to treat roundworms, hookworms and tapeworms
Deracoxib is a coxib class nonsteroidal anti-inflammatory drug (NSAID). [3] Like other NSAIDs, its effects are caused by inhibition of cyclooxygenase (COX) enzymes. [7] At the doses used to treat dogs, deracoxib causes greater inhibition of COX-2 than of COX-1, [3] but at doses twice those recommended for use in dogs, deracoxib significantly inhibits COX-1 as well.
[10] [15] New cutaneous or subcutaneous lumps, such as papillomas, can appear, [10] [17] and dogs face an increased susceptibility to infections such as demodicosis. [1] [15] There is a transient decrease in neutrophils, eosinophils, and monocytes, as well as in serum globulin, while cholesterol and lipase levels increase.
Capromorelin, sold under the brand names Entyce and Elura, is a medication used for the management of weight loss in cats and dogs. [5] [6] Capromorelin is a ghrelin receptor agonist known to increase appetite and weight gain. [2] Capromorelin was developed by Pfizer. [7] [8] Capromorelin was approved for veterinary use in the United States in ...
Grapiprant is widely accepted in veterinary medicine due to its specific and targeted approach to pain management in dogs. The serum concentration of grapiprant is increased when used in conjunction with other drugs such as acetaminophen, albendazole, and alitretinoin. [citation needed]
The use of tepoxalin was more effective than the NSAID (nonsteroidal anti-flammatory drug), carprofen when administered in canines. As a result, the usage of carprofen was replaced with tepoxalin in 1998. [6] Tepoxalin can only be administered to dogs that weigh 3 pounds (1.4 kg) or larger at a dose of 10–20 mg/kg at a daily schedule. [7]
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