Search results
Results from the WOW.Com Content Network
A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates. [1] Lymphocytes include T cells (for cell-mediated and cytotoxic adaptive immunity), B cells (for humoral, antibody-driven adaptive immunity), [2] [3] and innate lymphoid cells (ILCs; "innate T cell-like" cells involved in mucosal immunity and homeostasis), of which natural killer cells are an ...
IgM: Memory B cells that express IgM can be found concentrated in the tonsils, Peyer's patch, and lymph nodes. [3] This subset of memory B cells is more likely to proliferate and reenter the germinal center during a secondary immune response. [4] IgG: Memory B cells that express IgG typically differentiate into plasma cells. [4]
Some memory B cells can be activated without T cell help, such as certain virus-specific memory B cells, but others need T cell help. [26] Upon antigen binding, the memory B cell takes up the antigen through receptor-mediated endocytosis, degrades it, and presents it to T cells as peptide pieces in complex with MHC-II molecules on the cell ...
After entering a lymph node, they then enter a lymphoid follicle, where they multiply and divide, each producing a different antibody. If a cell is stimulated, it will go on to produce more antibodies (a plasma cell) or act as a memory cell to help the body fight future infection. [27] If a cell is not stimulated, it will undergo apoptosis and ...
A small, resting T lymphocyte rapidly undergoes blastogenic transformation into a large lymphocyte (13–15 μm). This large lymphocyte (known in this context as a lymphoblast) then divides several times to produce an expanded population of medium (9–12 μm) and small lymphocytes (5–8 μm) with the same antigenic specificity. [14]
Lymphocytes are distinguished by having a deeply staining nucleus that may be eccentric in location, and a relatively small amount of cytoplasm. Lymphocytes include: B cells make antibodies that can bind to pathogens, block pathogen invasion, activate the complement system, and enhance pathogen destruction. T cells:
The centrocytes to compete for T follicular helper cell and dendritic cell help, allowing for selectivity towards centrocytes that bind to antigen with higher affinity. Centrocytes with high affinity are allowed to exit the germinal center as memory B cells or long-lived plasma cells , while other selected centrocytes are allowed to reenter the ...
These cells were named central memory T cells (T CM). They effectively stimulate dendritic cells, and after repeated stimulation they are able to differentiate in CCR7- effector memory T cells. Both populations of these memory cells originate from naive T cells and remain in the body for several years after initial immunization. [14]