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Ankylosing spondylitis (AS) is a type of arthritis from the disease spectrum of axial spondyloarthritis. [5] It is characterized by long-term inflammation of the joints of the spine, typically where the spine joins the pelvis. [2] With AS, eye and bowel problems—as well as back pain—may occur. [2]
Among the Sami in Northern Scandinavia , 24% of people are HLA-B27 positive, while 1.8% have associated ankylosing spondylitis, [3] compared to 14-16% of Northern Scandinavians in general. [ 4 ] [ 5 ] In Finland, an estimated 14% of the population is positive for HLA-B27, while more than 95% of patients with ankylosing spondylitis and ...
Dagger sign is a radiologic sign seen in advanced cases of ankylosing spondylitis. [1] The appearance of a dagger is seen in the X-ray because of ossification of the supraspinous and infraspinous ligaments. [2] As a result, a central dense line of sclerosis, resembling a dagger can be seen in the AP radiograph of spine and pelvis. [3]
Since the disease ankylosing spondylitis was still defined by the Modified New York criteria of 1984, there was the need to find a new disease term that would also include the less severe forms or early onset of ankylosing spondylitis. This expression was found in the umbrella term axial spondyloarthritis.
HLA-B27 is a polymorphic form of the HLA-B molecule found in up to 95% of people with ankylosing spondylitis of European ancestry, [16] [17] 70% with reactive arthritis, [18] 60% with psoriatic spondylitis, [12] 25% with peripheral psoriatic arthritis, [17] and 70% with spondylitis associated with inflammatory bowel disease.
In 1994, a research team consisting of rheumatologists, physiotherapists, and others with a special interest in Ankylosing Spondylitis, developed the index in Bath, England (hence the reason for "Bath" in the name), describing a self-administered 6-question measurement tool that later become the gold standard for measuring and evaluating AS disease activity.
Spondylitis is an inflammation of the vertebrae. It is a form of spondylopathy . In many cases, spondylitis involves one or more vertebral joints , as well, which itself is called spondylarthritis .
Pages in category "Ankylosing spondylitis" The following 7 pages are in this category, out of 7 total. This list may not reflect recent changes. ...
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