Search results
Results from the WOW.Com Content Network
Lenalidomide, sold under the brand name Revlimid among others, is a medication used to treat multiple myeloma, smoldering myeloma, and myelodysplastic syndromes (MDS). [8] For multiple myeloma, it is a first line treatment, and is given with dexamethasone . [ 8 ]
Celgene Corporation is a pharmaceutical company that makes cancer and immunology drugs. Its major product is Revlimid (lenalidomide), which is used in the treatment of multiple myeloma, and also in certain anemias.
The thalidomide molecule is a synthetic derivative of glutamic acid and consists of a glutarimide ring and a phthaloyl ring (Figure 5). [15] [16] Its IUPAC name is 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione and it has one chiral center [15] After thalidomide's selective inhibition of TNF-α had been reported, a renewed effort was put in thalidomide's clinical development.
Steady state maximum concentration with low-fat meal conditions at the 400 mg once daily dose was found to be 2.1 ± 1.1 μg/mL. It is recommended that venetoclax be administered with a meal. [7] The apparent volume of distribution for venetoclax is approximately 256–321 L. It is highly bound to human plasma protein.
Lipinski's rule of five, also known as Pfizer's rule of five or simply the rule of five (RO5), is a rule of thumb to evaluate druglikeness or determine if a chemical compound with a certain pharmacological or biological activity has chemical properties and physical properties that would likely make it an orally active drug in humans.
The Ocala Demands was a platform for economic and political reform that was later adopted by the People's Party.In December, 1890, the National Farmers' Alliance and Industrial Union, more commonly known as the Southern Farmers' Alliance, its affiliate the Colored Farmers' Alliance, and the Farmers' Mutual Benefit Association met jointly in the Marion Opera House in Ocala, Florida, where they ...
Cannabis company Trulieve launched a new Yes On 3 line of marijuana products to support the ballot initiative to legalize adult recreational marijuana use in Florida.. The specialty products ...
According to the collective assets of the Florida Hurricane Catastrophe Fund, it is the second largest mandate of the SBA. Changes made by the Florida Legislature continue to improve the program's ability to meet its potential needs by reducing optional program coverage and gradually increasing its pricing to better reflect future claims. [3]