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Ototoxic drugs also may cause subjective tinnitus, as they may cause hearing loss, [15] or increase the damage done by exposure to loud noise. [38] This damage may occur even at doses not considered ototoxic. [39] More than 260 medications have been reported to cause tinnitus as a side effect. [40]
Cinnarizine's antagonistic effects of D2 dopamine receptors in the striatum leads to symptoms of depression, tremor, muscle rigidity, tardive dyskinesia, and akathisia. 17 of 100 new parkinsonism cases are linked to administration of either cinnarizine or flunarizine. [5] Drug induced parkinsonism is the second leading cause of parkinsonism. [22]
Ototoxicity is the property of being toxic to the ear (oto-), specifically the cochlea or auditory nerve and sometimes the vestibular system, for example, as a side effect of a drug. The effects of ototoxicity can be reversible and temporary, or irreversible and permanent. It has been recognized since the 19th century. [1] There are many well ...
1. antagonist. H1 antagonists, also called H1 blockers, are a class of medications that block the action of histamine at the H 1 receptor, helping to relieve allergic reactions. Agents where the main therapeutic effect is mediated by negative modulation of histamine receptors are termed antihistamines; other agents may have antihistaminergic ...
Chemotherapy Drug Could Have A Serious And Surprising Side Effect, Study Finds Tedeschi emphasized the importance of wearing proper hearing protection, like ear buds and earmuffs, both in and out ...
Ménière's disease (MD) is a disease of the inner ear that is characterized by potentially severe and incapacitating episodes of vertigo, tinnitus, hearing loss, and a feeling of fullness in the ear. [3][4] Typically, only one ear is affected initially, but over time, both ears may become involved. [3] Episodes generally last from 20 minutes ...
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