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Acral lentiginous melanoma. Acral lentiginous melanoma is a type of skin cancer. [6] It typically begins as a uniform brownish mark before becoming darker and wider with a blurred irregular edge, most frequently seen in the foot of a person with darker skin. [6] It may become bumpy and ulcerate. [6]
An acral nevus is a cutaneous condition of the palms, soles, fingers, or toes (peripheral body parts), characterized by a skin lesion that is usually macular or only slightly elevated, and may display a uniform brown or dark brown color, often with linear striations. [1]: 1726. Acral nevi may occur in all ethnic groups, but are more common in ...
Peeling skin syndrome 5 is caused by a genetic defect in the serpin (serpin family member 8) gene. This gene is produced by platelets and can bind to and inhibit the function of furin, which is a serine protease involved in platelet functions. It is also characterized by superficial peeling of the dorsal and palmar pores and skin of the hands ...
Acral necrosis is a symptom common in bubonic plague. The striking black discoloration of skin and tissue, primarily on the extremities ("acral"), is commonly thought to have given rise to the name " Black Death ," associated both with the disease and the pandemic which occurred in the 14th century.
Dermatology. Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients ...
Rare. Primary cutaneous acral CD8 positive T cell lymphoproliferative disorder ( CD8+ TLPD) is one type of the lymphoproliferative disorders in which a slow-growing nodule or papule develops on the ear or, less commonly, other acral sites. CD8 positive T-cells (i.e., CD8+ T-cells) are a subtype of the lymphocytes and acral sites are peripheral ...
Melanocytic nevus. A melanocytic nevus (also known as nevocytic nevus, nevus-cell nevus and commonly as a mole) [1][2] is usually a noncancerous condition of pigment-producing skin cells. It is a type of melanocytic tumor that contains nevus cells. [2] A mole can be either subdermal (under the skin) or a pigmented growth on the skin, formed ...
Acromegaly is a disorder that results in excess growth of certain parts of the human body. It is caused by excess growth hormone (GH) after the growth plates have closed. The initial symptom is typically enlargement of the hands and feet. [3] There may also be an enlargement of the forehead, jaw, and nose.