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The agouti factor determines the "background" of the tabby coat, which consists of hairs that are banded with dark eumelanin and lighter phaeomelanin along the length of the hair shaft. The Agouti gene , with its dominant A allele and recessive a allele, controls the coding for agouti signaling protein (ASIP; Q865F0 ).
An agouti dog, also called wolf sable. In dogs, the agouti gene is associated with various coat colors and patterns. [10]The alleles at the A locus are related to the production of agouti-signaling protein (ASIP) and determine whether an animal expresses an agouti appearance and, by controlling the distribution of pigment in individual hairs, what type of agouti.
A cat hair showing agouti coloration A domestic rabbit with agouti coloration. Agouti is a type of fur coloration in which each hair displays two or more bands of pigmentation. [1] [2] The overall appearance of agouti fur is usually gray or dull brown, [3] although dull yellow is also possible.
Two distinct gene loci, the agouti gene locus (two alleles) and the tabby locus (three alleles), and one modifier, spotted (two alleles), cause the four basic tabby patterns. The fifth pattern is emergent, being expressed by female cats with one black and one orange gene on each of their two X chromosomes, and is explained by Barr bodies and ...
The mane, tail, and ear rims are referred to as "trim" and roughly correspond to the "points" of horses. Most donkeys have light points. The coat colors without light points may be called "no light points", "dark points", or "black points". Dark points are caused by a recessive allele of agouti found in Normand and Miniature donkeys.
The lynx point pattern is formed by mating a colorpoint cat with a tabby cat (or breeding cats that already possess the lynx point pattern). It is characterized by a mixture of the darkening (reduced) of point coloration with distinct tabby striping on the head, tail, and legs, and an otherwise uniform and comparatively pale body.
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Agouti-signaling protein is a protein that in humans is encoded by the ASIP gene. [5] [6] It is responsible for the distribution of melanin pigment in mammals.[7] [8] Agouti interacts with the melanocortin 1 receptor to determine whether the melanocyte (pigment cell) produces phaeomelanin (a red to yellow pigment), or eumelanin (a brown to black pigment). [9]