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Necrotizing fasciitis (NF), also known as flesh-eating disease, is an infection that kills the body's soft tissue. [3] It is a serious disease that begins and spreads quickly. [ 3 ] Symptoms include red or purple or black skin, swelling, severe pain, fever , and vomiting. [ 3 ]
An Indianapolis woman died two months after contracting necrotizing fasciitis, commonly known as flesh-eating bacteria, while in Florida.
Fasciitis is an inflammation of the fascia, [1] which is the connective tissue surrounding muscles, blood vessels and nerves. In particular, it often involves one of the following diseases: Necrotizing fasciitis
It’s the most common cause of necrotizing fasciitis, the CDC notes. Healthy people can get streptococcal necrotizing fasciitis, but it most commonly affects people who have a weakened immune ...
impetigo, cellulitis, and erysipelas – infections of the skin which can be complicated by necrotizing fasciitis – skin, fascia and muscle; strep throat AKA strep pharyngitis – pharynx; Less common: bacteremia can be associated with these infections, but is not typical. septic arthritis – joints; osteomyelitis – bones
The bacteria, which causes necrotizing fasciitis, has an extremely high mortality rate, and accurate diagnosis, rapid antibiotic administration and prompt surgery are extremely important in ...
The affected tissue of patients with severe cases of necrotizing fasciitis are devoid of neutrophils. [27] The serine protease ScpC, which is released by S. pyogenes, is responsible for preventing the migration of neutrophils to the spreading infection. ScpC degrades the chemokine IL-8, which would otherwise attract neutrophils to the site of ...
Infections which are in the deep tissues (necrotizing cellulitis, fasciitis and myositis) often include Clostridium spp., S. pyogenes or polymicrobic combinations of both aerobic and anaerobic bacteria. Gas in the tissues and putrid-like pus with a gray thin quality are often found in these infections, and they are frequently associated with a ...