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Empagliflozin is an inhibitor of the sodium glucose co-transporter-2 (SGLT-2), and works by increasing sugar loss in urine. [2] Empagliflozin was approved for medical use in the United States and in the European Union in 2014. [13][23][24] It is on the World Health Organization's List of Essential Medicines. [25]
In June 2023, the US Food and Drug Administration (FDA) expanded the indication, as an addition to diet and exercise, to improve blood sugar control in children 10 years and older with type 2 diabetes.
Paroxetine, sold under the brand name Paxil among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [7] It is used to treat major depressive disorder, obsessive-compulsive disorder, panic disorder, social anxiety disorder, post-traumatic stress disorder, generalized anxiety disorder, and premenstrual dysphoric disorder. [7]
Vortioxetine. Vortioxetine, sold under the brand name Trintellix (in the US) and Brintellix (in the EU) among others, is an antidepressant of the serotonin modulator and stimulator (SMS) class. [15][3] Its effectiveness is viewed as similar to that of other antidepressants. [15] It is taken orally.
In 2012, metoclopramide was one of the top 100 most prescribed medications in the United States. [9] It is available as a generic medication. [6] It is on the World Health Organization's List of Essential Medicines. [10] In 2020, it was the 352nd most commonly prescribed medication in the United States, with more than 600,000 prescriptions. [11]
The Top 100 Drugs: Clinical Pharmacology and Practical Prescribing is a pocket-size medical manual focusing on the most commonly prescribed medicines by the British National Health Service (NHS). It was first published by Churchill Livingstone , Elsevier , in 2014, revised in a second edition in 2018, and again in 2022 in a third edition.
The CPhA is a nonprofit organization that advocates for pharmacists in Canada. An external Editorial Advisory Committee of Canadian physicians and pharmacists advises CPhA about the strategic direction of their publications including CPS. CPS is also available online by subscription at www.pharmacists.ca. Most of the drug monographs in CPS are ...
Rank Brand Name(s) Generic Name Sales Q1 2014 Sales ($000) Change from Q4 2013 Company(ies) Disease/Medical Use First Approval Date Patent Expiration Date [6] [7]; 1: Abilify