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  2. Opiorphin - Wikipedia

    en.wikipedia.org/wiki/Opiorphin

    Such action extends the duration of enkephalin effect where the natural pain killers are released physiologically in response to specific potentially painful stimuli, in contrast with administration of narcotics, which floods the entire body and causes many undesirable adverse reactions, including addiction liability and constipation.

  3. Phenoperidine - Wikipedia

    en.wikipedia.org/wiki/Phenoperidine

    Phenoperidine was first synthesized in 1957 by Paul Janssen, of the company now known as Janssen Pharmaceutica, who was seeking better opioid pain-killers. [5] His two prototype drugs were methadone and pethidine , each which had been invented in 1930s by Otto Eisleb, who worked for IG Farben .

  4. Nimesulide - Wikipedia

    en.wikipedia.org/wiki/Nimesulide

    Nimesulide is a nonsteroidal anti-inflammatory drug (NSAID) with pain medication and fever reducing properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis, and primary dysmenorrhoea in adolescents and adults above 12 years old. Side effects may include liver problems. [1]

  5. FDA approves new pain medication as an alternative to ... - AOL

    www.aol.com/news/fda-approves-pain-medication...

    Acute pain is something more than 80 million Americans fill prescriptions to treat each year, according to Vertex. As opposed to chronic pain, which can last well after an injury or illness has ...

  6. Pentazocine - Wikipedia

    en.wikipedia.org/wiki/Pentazocine

    Pentazocine, [3] sold under the brand name Talwin among others, is an analgesic medication used to treat moderate to severe pain. It is believed to work by activating (agonizing) κ-opioid receptors (KOR) and μ-opioid receptors (MOR).

  7. FDA approves painkiller designed to eliminate the risk of ...

    www.aol.com/news/fda-approves-painkiller...

    Studies in more than 870 patients with acute pain due to foot and abdominal surgeries showed Vertex's drug provided more relief than a dummy pill but didn't outperform a common opioid ...

  8. Metamizole - Wikipedia

    en.wikipedia.org/wiki/Metamizole

    Metamizole, with its potent analgesic (pain relief), antipyretic (fever reduction), and spasmolytic (relax muscle contractions) properties, is utilized in the management of acute pain, fever, and pain caused by muscle spasms.

  9. The best muscle pain relief creams of 2025, according to ...

    www.aol.com/lifestyle/best-muscle-pain-relief...

    Cost: $7 | Active ingredients: Lidocaine | Type: Cream | Amount: 4.3 ounces. Lidocaine is another popular ingredient found in pain relief creams. It's a topical anesthetic that's often used to ...

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