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Ponazuril (), sold by Merial, Inc., [1] now part of Boehringer Ingelheim, [2] under the trade name Marquis (15% w/w ponazuril), is a drug currently approved for the treatment of equine protozoal myeloencephalitis (EPM) in horses, caused by coccidia Sarcocystis neurona.
The Dosage Index is a mathematical figure used by breeders of Thoroughbred race horses, and sometimes by bettors handicapping horse races, to quantify a horse's ability, or inability, to negotiate the various distances at which horse races are run. It is calculated based on an analysis of the horse's pedigree.
Its use as a performance-enhancing substance in horse racing has also been suspected and similar tests have been developed for horses [3] ITPP has been studied for potential adjuvant use in the treatment of cancer in conjunction with chemotherapy , due to its effects in reducing tissue hypoxia . [ 4 ]
Detomidine is a sedative with analgesic properties. [3] α 2-adrenergic receptor agonists produce dose-dependent sedative and analgesic effects, mediated by activation of α 2 catecholamine receptors, thus inducing a negative feedback response, reducing production of excitatory neurotransmitters.
Equine drug testing is a form of drug testing applied to performance horses in regulated competition. Most common in racehorses , drug tests are also performed on horses in endurance riding and in international competition such as the Olympics and FEI -sanctioned competition.
The above photo shows the positive results of the number 2 Marquis reagent presumptive drug test when used with a sample of opium. It is the primary presumptive test used in Ecstasy reagent testing kits. It can also be used to test for such substances as opiates (e.g. codeine, heroin), and phenethylamines (e.g. 2C-B, mescaline).
Grass is a natural source of nutrition for a horse. Equine nutrition is the feeding of horses, ponies, mules, donkeys, and other equines. Correct and balanced nutrition is a critical component of proper horse care. Horses are non-ruminant herbivores of a type known as a "hindgut fermenter." Horses have only one stomach, as do humans.
Butorphanol is a narcotic used for pain relief in horses. [15] It is administered either IM or IV, with its analgesic properties beginning to take effect about 15 minutes after injection and lasting 4 hours. [16] It is also commonly paired with sedatives, such as xylazine and detomidine, to make the horse easier to handle during veterinary ...
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