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Lipohypertrophy [1] is a lump under the skin caused by accumulation of extra fat at the site of many subcutaneous injections of insulin. It may be unsightly, mildly painful, and may change the timing or completeness of insulin action. It is a common, minor, chronic complication of diabetes mellitus.
This insulin is referred to as basal insulin secretion, and constitutes almost half [1] the insulin produced by the normal pancreas. Bolus insulin is produced during the digestion of meals. Insulin levels rise immediately as we begin to eat, remaining higher than the basal rate for 1 to 4 hours.
In many people, both a rapid- or short-acting insulin product as well as an intermediate- or long-acting product are used to decrease the amount of injections per day. In some, insulin injections may be combined with other injection therapy such as GLP-1 receptor agonists. Cleansing of the injection site and injection technique are required to ...
Eli Lilly’s experimental insulin that is injected just once a week is as effective as daily insulin injections for maintaining blood sugar levels in patients with type 1 or type 2 diabetes ...
The latest clinical trial results from Eli Lilly show the drug manufacturer's once-weekly insulin injection is just as effective as daily insulin shots for managing A1C levels in diabetes. Experts ...
In the early days of insulin treatment for type 1 diabetes there was much debate as to whether strict control of hyperglycaemia would delay or prevent the long-term complications of diabetes. The work of Pirart [50] suggested that microvascular complications of diabetes were less likely to occur in individuals with better glycaemic control.
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