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One study among 96 patients diagnosed with gestational diabetes in the last three years found that, compared to insulin therapy, metformin had superior effects on blood sugar levels, inflammation ...
Some researchers are investigating how metformin, a common drug used to treat diabetes, may help prolong healthspan and lifespan. What evidence is there to support this notion?
If you’ve been prescribed metformin, it may be because you have prediabetes, type 2 diabetes, gestational diabetes, weight gain issues caused by antipsychotic medication or polycystic ovary ...
Although it must be used with caution in patients with impaired liver or kidney function, Metformin, a biguanide, has become the most commonly used agent for type 2 diabetes in children and teenagers. Among common diabetic drugs, Metformin is the only widely used oral drug that does not cause weight gain. [9]
[233] [235] Whether metformin may help extend life, even in otherwise healthy people, remains unknown; a 2021 review of the literature found it is likely to improve healthspan, i.e., the number of years spent in good health, rather than lifespan overall. [236]
It is important for patients to eat 3 meals a day as well in order to reduce the chances of hypoglycemia, especially with patients that take insulin. [ 1 ] There is a lack of evidence of the usefulness of low-carbohydrate dieting for people with type 1 diabetes (T1D). [ 20 ]
In those with prediabetes, metformin may delay or reduce the risk of developing type 2 diabetes compared to diet and exercise or a placebo intervention, but not compared to intensive diet and exercise, and there was not enough data on outcomes such as mortality and diabetic complications and health-related quality of life, according to a 2019 ...
Extend health span by reducing the risk of disease at the end of life Be tested for safety and efficacy on hundreds, possibly thousands of people in clinical trials Influence all-cause mortality