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In this study, in vitro toxicity of N-isopropylbenzylamine and its toxicity-related targets were investigated in SN4741, SH-SY5Y or PC12 cell lines that model neurons. The study sounds an alarm for methamphetamine users and warns of the dangers of N-isopropylbenzylamine for public health. [2] Isopropylbenzylamine hydrochloride crystals seized ...
Propylamine, also known as n-propylamine, is an amine with the chemical formula CH 3 (CH 2) 2 NH 2. [1] It is a colorless volatile liquid. [2] Propylamine is a weak base. Its K b (base dissociation constant) is 4.7 × 10 −4.
Aminomethyl propanol is used for the preparation of buffer solutions. [3] It is a component of the drugs ambuphylline and pamabrom. It is also used in cosmetics. [2] It is a precursor to oxazolines via its reaction with acyl chlorides. [5] Via sulfation of the alcohol, the compound is also a precursor to 2,2-dimethylaziridine. [6]
Isopropylamine can be obtained by reaction of isopropyl alcohol with ammonia in presence of a catalyst: [3] (CH 3) 2 CHOH + NH 3 → (CH 3) 2 CHNH 2 + H 2 O. Isopropylamine is a building block for the preparation of many herbicides and pesticides including atrazine, bentazon, glyphosate, imazapyr, ametryne, desmetryn, prometryn, pramitol, dipropetryn, propazine, fenamiphos, and iprodione. [3]
N,N-Diisopropylethylamine, or Hünig's base, is an organic compound that is a tertiary amine. It is named after the German chemist Siegfried Hünig . It is used in organic chemistry as a non-nucleophilic base. It is commonly abbreviated as DIPEA, DIEA, or i-Pr 2 NEt.
It is the N-benzyl derivative of 3,4-methylenedioxyamphetamine (MDA). MDBZ was first synthesized by Alexander Shulgin . In his book PiHKAL (Phenethylamines i Have Known And Loved) , the minimum dosage is listed as 150 mg, and the duration unknown.
tert-Butanesulfinamide (also known as 2-methyl-2-propanesulfinamide or Ellman's sulfinamide) is an organosulfur compound and a member of the class of sulfinamides. Both enantiomeric forms are commercially available and are used in asymmetric synthesis as chiral auxiliaries , often as chiral ammonia equivalents for the synthesis of amines .
[3] [4] These are further deaminated by CYP2C in liver transforming them into inactive 1-(Thiophen-2-yl)-2-propan-2-one which is a phenylacetone derivative. [5] Propan-2-amines are not metabolized by monoamine oxidases and most actually behave as competitive monoamine oxidase inhibitors .