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Frontotemporal dementia (FTD), also called frontotemporal degeneration disease [1] or frontotemporal neurocognitive disorder, [2] encompasses several types of dementia involving the progressive degeneration of the brain's frontal and temporal lobes. [3] Men and women appear to be equally affected. [1]
The three clinical subtypes of frontotemporal lobar degeneration, frontotemporal dementia, semantic dementia and progressive nonfluent aphasia, are characterized by impairments in specific neural networks. [17] The first subtype, frontotemporal dementia, mainly affects a frontomedian network and impairs social cognition.
Frontotemporal dementia, or FTD, is a rare disease that affects parts of the brain controlling behavior and language. These parts of the brain shrink as the disease gets worse. These parts of the ...
The hallmark symptom of LATE is a progressive memory loss that predominantly affects short-term and episodic memory. [1] This impairment is often severe enough to interfere with daily functioning and usually remains the chief neurologic deficit, unlike other types of dementia in which non-memory cognitive domains and behavioral changes might be noted earlier or more prominently. [1]
Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) is an autosomal dominant neurodegenerative tauopathy and Parkinson plus syndrome. [3] FTDP-17 is caused by mutations in the MAPT (microtubule associated protein tau) gene located on the q arm of chromosome 17, and has three cardinal features: behavioral and personality changes, cognitive impairment, and motor symptoms.
Future research into causes of Alzheimer’s disease. Currently, physicians don’t routinely request genetic testing for people diagnosed with Alzheimer’s. The study authors say this type of ...
Consequently, people with vascular dementia tend to perform worse than their Alzheimer's disease counterparts in frontal lobe tasks, such as verbal fluency, and may present with frontal lobe problems: apathy, abulia (lack of will or initiative), problems with attention, orientation, and urinary incontinence.
Alzheimer's disease (AD) is a chronic neurodegenerative disease that results in the loss of neurons and synapses in the cerebral cortex and certain subcortical structures, resulting in gross atrophy of the temporal lobe, parietal lobe, and parts of the frontal cortex and cingulate gyrus. [14]
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