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A drug holiday (sometimes also called a drug vacation, medication vacation, structured treatment interruption, tolerance break, treatment break or strategic treatment interruption) is when a patient stops taking a medication(s) for a period of time; anywhere from a few days to many months or even years if the doctor or medical provider feels it is best for the patient.
Anthracyclines remain some of the most widely used chemotherapeutic agents but their potential is limited by its dose-limiting toxicities. Currently, there are many studies being conducted in the search for anthracyclines with better anti-tumour efficacy or with reduced side effects using different nanotechnology-based drug delivery systems.
Pharmacological Reviews is a quarterly peer-reviewed scientific journal publishing review articles on all aspects of pharmacology and related topics. It is published by the American Society for Pharmacology and Experimental Therapeutics. The editor-in-chief is Lynette C. Daws (The University of Texas Health Science Center at San Antonio).
Muscle relaxation and paralysis can theoretically occur by interrupting function at several sites, including the central nervous system, myelinated somatic nerves, unmyelinated motor nerve terminals, nicotinic acetylcholine receptors, the motor end plate, and the muscle membrane or contractile apparatus.
Drug antagonism refers to a medicine stopping the action or effect of another substance, preventing a biological response. [1] [2] The stopping actions are carried out by four major mechanisms, namely chemical, pharmacokinetic, receptor and physiological antagonism. [2]
The wavy line between α carbon and CH 3 group indicates isomerism; ... Katzung, Bertram G. (2009). Basic & clinical pharmacology. 11th edition. McGraw-Hill Medical.
President Donald Trump’s executive order grasping far greater control over independent federal agencies embraces a constitutionally questionable theory that presidents dating back to Ronald ...
A review found that when erythromycin was given with certain oral contraceptives, there was an increase in the maximum serum concentrations and AUC of estradiol and dienogest. [32] [33] Erythromycin is an inhibitor of the cytochrome P450 system, which means it can have a rapid effect on levels of other drugs metabolised by this system, e.g ...