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Little is known about the long-term side effects of hormone or puberty blockers in children with gender dysphoria. Although puberty blockers are known to be safe and physically reversible treatment if stopped in the short term, it is also not known whether hormone blockers affect the development of factors like bone mineral density, brain ...
Based on current evidence, it's impossible to say whether puberty blockers and hormone therapy are helpful or harmful for young people with gender-related distress, according to two new papers ...
“Puberty blockers are sort of like a man-made hormone analogue, and basically what they do is fool the brain into not sending messages to the ovaries and testes to secrete hormones,” said Dr ...
It is also a steroid that blocks the effects of the hormones aldosterone and, to a lesser degree, testosterone, causing some estrogen-like effects. [ 25 ] [ unreliable source? ] [ 26 ] [ 27 ] [ unreliable medical source? ] [ 4 ] [ 28 ] Spironolactone belongs to a class of medications known as potassium-sparing diuretics .
Researchers have recommended puberty blockers after age 12, when the person has developed to Tanner stages 2–3, and then cross-sex hormones treatment at age 16. This use of the drug is off-label, however, not having been approved by the Food and Drug Administration and without data on long-term effects of this use. [needs update] [18]
Breen’s suit claims Olson-Kennedy’s clinic put her on puberty blockers when she was just 12, started her on hormone therapy at 13 and performed a double mastectomy on her at 14.
Antiandrogens, also known as androgen antagonists or testosterone blockers, are a class of drugs that prevent androgens like testosterone and dihydrotestosterone (DHT) from mediating their biological effects in the body. They act by blocking the androgen receptor (AR) and/or inhibiting or suppressing androgen production.
When are puberty blockers needed? Considerable effort goes into deciding whether children under age 8 who are showing symptoms might benefit from the injectable hormone treatments, pediatric ...