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Optic neuritis: Either 1) brain MRI showing normal findings or only nonspecific white matter lesions, or 2) optic nerve MRI showing T2-hyperintensity, or T1 enhancing lesion, greater than 1/2 optic nerve length or involving optic chiasm Acute myelitis: intramedullary lesion > 3 contiguous segments, or spinal atrophy ≥ 3 contiguous segments
Magnetic Resonnance Imaging (MRI) during an episode of optic neuritis. Advanced imaging using optical coherence tomography (OCT) is very sensitive reveal damage to the optic nerve. The OCT shows corresponding optic disc swelling acutely or an inter-eye difference in the thickness of the neurons and their nerves connecting the eye with the brain ...
Magnetic resonance imaging can capture optic nerve inflammation, but this finding is not present in all patients, [1] [3] [13] Diffusion tensor imaging has been shown to detect widespread white matter abnormalities in CRION patients with normal MRI findings. [14] Five diagnostic criteria had been proposed in 2014: [3] History of optic neuritis ...
Lesions involving the whole optic nerve cause complete blindness on the affected side, that means damage at the right optic nerve causes complete loss of vision in the right eye. [3] Optic neuritis involving external fibers of the optic nerve causes tunnel vision. [4] Optic neuritis involving internal fibers of the optic nerve causes central ...
Optic neuritis, when combined with the presence of multiple demyelinating white matter brain lesions on MRI, is suspicious for multiple sclerosis. Several causes and clinical courses are possible for the optic neuritis. It can be classified in: Single isolated optic neuritis (SION) relapsing isolated optic neuritis (RION)
Retrobulbar neuritis, an inflamed optic nerve, but with a normal-appearing nerve head, is associated with pain and the other findings of papillitis. Pseudopapilledema is a normal variant of the optic disk , in which the disk appears elevated, with indistinct margins and a normal vascular pattern.
Transverse myelitis (TM) is a rare neurological condition wherein the spinal cord is inflamed.The adjective transverse implies that the spinal inflammation extends horizontally throughout the cross section of the spinal cord; [1] the terms partial transverse myelitis and partial myelitis are sometimes used to specify inflammation that affects only part of the width of the spinal cord. [1]
Devic's disease and neuromyelitis optica (NMO) (sometimes previously called optic-spinal MS) Acute disseminated encephalomyelitis or ADEM, a closely related disorder in which a known virus or vaccine triggers autoimmunity against myelin. Acute hemorrhagic leukoencephalitis, possibly a variant of Acute disseminated encephalomyelitis
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