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  2. Lactic acidosis - Wikipedia

    en.wikipedia.org/wiki/Lactic_acidosis

    Lactic acidosis refers to the process leading to the production of lactate by anaerobic metabolism. It increases hydrogen ion concentration tending to the state of acidemia or low pH. The result can be detected with high levels of lactate and low levels of bicarbonate. This is usually considered the result of illness but also results from ...

  3. Metabolic myopathy - Wikipedia

    en.wikipedia.org/wiki/Metabolic_myopathy

    People with a metabolic myopathy often experience symptoms such as: Exercise intolerance, [citation needed] Abnormal muscle fatigue (premature fatigue and/or inability to get into second wind), muscle pain (myalgia), cramping or muscle stiffness during and/or after exercise, [citation needed] Shortness of breath (dyspnea), or rapid breathing ...

  4. MELAS syndrome - Wikipedia

    en.wikipedia.org/wiki/MELAS_syndrome

    MELAS is a condition that affects many of the body's systems, particularly the brain and nervous system (encephalo-) and muscles (myopathy). In most cases, the signs and symptoms of this disorder appear in childhood following a period of normal development. [4] Children with MELAS often have normal early psychomotor development until the onset ...

  5. Mitochondrial myopathy - Wikipedia

    en.wikipedia.org/wiki/Mitochondrial_myopathy

    Proximal muscle weakness, exercise intolerance, lactic acidosis, high serum lactate/pyruvate ratio, normal to elevated serum CK, dyspnea, exaggerated cardiorespiratory response to exercise are common symptoms. It may be isolated to the muscle (pure myopathy) or may be systemic including not only myopathy, but also eye abnormalities, peripheral ...

  6. When Is the Best Time to Take Metformin? - AOL

    www.aol.com/best-time-metformin-141700387.html

    The condition occurs when there’s a buildup of lactic acid in the bloodstream. Symptoms of lactic acidosis include nausea, vomiting, and weakness. Symptoms of lactic acidosis include nausea ...

  7. Pyruvate carboxylase deficiency - Wikipedia

    en.wikipedia.org/wiki/Pyruvate_carboxylase...

    Pyruvate carboxylase deficiency is an inherited disorder that causes lactic acid to accumulate in the blood. [2] High levels of these substances can damage the body's organs and tissues, particularly in the nervous system. Pyruvate carboxylase deficiency is a rare condition, with an estimated incidence of 1 in 250,000 births worldwide.

  8. Why You Feel That Burning Sensation in Your Legs During Hard ...

    www.aol.com/why-feel-burning-sensation-legs...

    Lactate as the byproduct of intense exercise is often to blame for the burning muscle sensation. “The issue is that when you move lactate around, it moves hydrogen ions around with it, and those ...

  9. Metabolic acidosis - Wikipedia

    en.wikipedia.org/wiki/Metabolic_acidosis

    Generally, metabolic acidosis occurs when the body produces too much acid (e.g., lactic acidosis, see below section), there is a loss of bicarbonate from the blood, or when the kidneys are not removing enough acid from the body. Chronic metabolic acidosis is most often caused by a decreased capacity of the kidneys to excrete excess acids ...

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