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Gerhard Johannes Paul Domagk (German pronunciation: [ˈɡeːɐ̯haʁt ˈdoːmak] ⓘ; 30 October 1895 – 24 April 1964) was a German pathologist and bacteriologist.. He is credited with the discovery of sulfonamidochrysoidine (KL730) as an antibiotic for which he received the 1939 Nobel Prize in Physiology or Medicine.
An open circulatory system is made up of a heart, vessels, and hemolymph. This diagram shows how the hemolymph is circulated throughout the body of a grasshopper. The hemolymph is first pumped through the heart, into the aorta, dispersed into the head and throughout the hemocoel, then back through the ostia that are located in the heart, where ...
The Cypro-Minoan syllabary (CM), more commonly called the Cypro-Minoan Script, is an undeciphered syllabary used on the island of Cyprus and at its trading partners during the late Bronze Age and early Iron Age (c. 1550–1050 BC).
Protein C, also known as autoprothrombin IIA and blood coagulation factor XIV, [5]: 6822 [6] is a zymogen, that is, an inactive enzyme. The activated form plays an important role in regulating anticoagulation , inflammation , and cell death and maintaining the permeability of blood vessel walls in humans and other animals.
Charles Louis Alphonse Laveran (18 June 1845 – 18 May 1922) was a French physician who won the Nobel Prize in Physiology or Medicine in 1907 for his discoveries of parasitic protozoans as causative agents of infectious diseases such as malaria and trypanosomiasis.
Therefore, a group of researchers aimed at finding potent, selective ACE inhibitors that would not contain a mercapto (SH) function and would have a weaker chelating function. They returned to work with carboxyl compounds and started working with substituted N -carboxymethyl-dipeptides as a general structure (R-CHCOOH-A 1 -A 2 ).
This is a controversial point, some assign COX 1 as the major prostacyclin producing cyclooxygenase in the endothelial cells of the blood vessels. [15] The series-3 prostaglandin PGH 3 also follows the prostacyclin synthase pathway, yielding another prostacyclin, PGI 3. [16] The unqualified term 'prostacyclin' usually refers to PGI 2.
Prostaglandins have been found in almost every tissue in humans and other animals. They are derived enzymatically from the fatty acid arachidonic acid. [2] Every prostaglandin contains 20 carbon atoms, including a 5-carbon ring. They are a subclass of eicosanoids and of the prostanoid class of fatty acid derivatives.