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NFAT-dependent promoters and enhancers tend to have 3-5 NFAT binding sites which indicates that higher order synergistic interactions between relevant proteins in a cooperative complex is needed for effective transcription. The best known class of these complexes is composed of NFAT and AP-1 or other bZIP proteins. This NFAT:AP-1 complex binds ...
The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component.
The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex.
Among the different forms of NFAT, NFAT5 is an important component of the hyperosmolar stress response system. [8] cDNA of NFAT5 was first isolated from a human brain cDNA library. Subsequent analysis revealed that NFAT5 is a member of the Rel family, which also consists of NF-κB and NFATc proteins. The largest Rel protein, it consists of ...
In NEET (UG) 2024 exam, for which a little more than 24 lakh registered, the paper was leaked on 5 May 2024 in Patna, Bihar. According to the police, the paper leak mafia allegedly took ₹30 lakhs to ₹50 lakhs from many candidates and accommodated them in the lodges of Patna where they were provided question papers, claiming to be that of ...
Alpha-actinin-3, also known as alpha-actinin skeletal muscle isoform 3 or F-actin cross-linking protein, is a protein that in humans is encoded by the ACTN3 gene (named sprinter gene, speed gene or athlete gene) located on chromosome 11.
In Northern Ireland, the equivalent of Reception is "P1", and the equivalent of the English Year 1 "P2", while the first year of secondary school is known as Year 8 or first year (rather than Year 7 as in England), and following that Lower and Upper Sixth are Year 13 and Year 14 respectively.
Sixth grade (also 6th grade or grade 6) is the sixth year of formal or compulsory education.Students in sixth grade are usually 12-13 years old. It is commonly the first or second grade of middle school or the last grade of elementary school, and the sixth school year since kindergarten.