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A cyanotic heart defect is any congenital heart defect (CHD) that occurs due to deoxygenated blood bypassing the lungs and entering the systemic circulation, or a mixture of oxygenated and unoxygenated blood entering the systemic circulation.
[82] [12] About 1 in 100 newborns is diagnosed with a congential heart defect, of which 10% are diagnosed with TOF. [12] Genetically, it is most commonly associated with Down syndrome and DiGeorge syndrome. [5] [24] Down syndrome and other chromosomal disorders are known to occur alongside congential heart defects such as TOF. [12]
Cyanotic heart disease, which is a category of congenital heart defect that results in low levels of oxygen in the blood. [2] This can be caused by either reduced blood flow to the lungs or mixing of oxygenated and deoxygenated blood. [2] Methemoglobinemia, which is a disease
Most congenital heart defects are not associated with other diseases. [3] A complication of CHD is heart failure. [2] Congenital heart defects are the most common birth defect. [3] [11] In 2015, they were present in 48.9 million people globally. [8] They affect between 4 and 75 per 1,000 live births, depending upon how they are diagnosed.
If left untreated, the disease may progress from left-to-right shunt (acyanotic heart) to right-to-left shunt (cyanotic heart), called Eisenmenger's syndrome. Pulmonary hypertension is a potential long-term outcome, which may require a heart and/or lung transplant. Another complication of PDA is intraventricular hemorrhage. [citation needed]
Total anomalous pulmonary venous connection, also known as total anomalous pulmonary venous return, is a rare cyanotic congenital heart defect in which the pulmonary veins drain into the right side of the heart instead of the left, as is usually seen. This can happen within the heart (intracardiac) where it drains into the coronary sinus or ...
The most common cause of right-to-left shunt is the Tetralogy of Fallot, a congenital cardiac anomaly characterized by four co-existing heart defects. Pulmonary stenosis (narrowing of the pulmonary valve and outflow tract, obstructing blood flow from the right ventricle to the pulmonary artery)
A hyperoxia test is a test that is performed—usually on an infant—to determine whether the patient's cyanosis is due to lung disease or a problem with blood circulation. It is performed by measuring the arterial blood gases of the patient while they breathe room air, then re-measuring the blood gases after the patient has breathed 100% ...