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An applied example is a synthesis of sunitinib begins by mixing 5-fluoroisatin slowly into hydrazine hydrate. [9] After 4 hours at 110 °C, the indole ring structure has been broken into (2-amino-5-fluoro-phenyl)-acetic acid hydrazide with reduction of the ketone at the 3-position.
Hydrochlorothiazide, sold under the brand name Hydrodiuril among others, is a diuretic medication used to treat hypertension and swelling due to fluid build-up. [4] Other uses include treating diabetes insipidus and renal tubular acidosis and to decrease the risk of kidney stones in those with a high calcium level in the urine. [4]
Headache, poor concentration, weight gain, poor memory, insomnia, and depression have all been associated with isoniazid use. [41] [42] All patients and healthcare workers should be aware of these serious side effects, especially if suicidal ideation or behavior are suspected. [41] [43] [44]
Weight gain. Some side effects, such as weight gain, occur more frequently with certain types of antidepressant medication. Switching to a new type of antidepressant may help reverse any weight ...
p-Toluenesulfonyl hydrazide is the organic compound with the formula CH 3 C 6 H 4 SO 2 NHNH 2. It is a white solid that is soluble in many organic solvents but not water or alkanes. It is a white solid that is soluble in many organic solvents but not water or alkanes.
Exceeding this amount may increase your risk of side effects, both from Viagra and from alcohol. Drinking might make your ED symptoms worse. We’ve all heard of whiskey privates.
Prolonged treatment may cause a syndrome similar to lupus, which can become fatal if the symptoms are not noticed and drug treatment stopped. [13] Hydralazine is within the top three drugs that is known to induce systemic lupus and this adverse drug event is dose dependent yet significant.
Typically 5-10 units of ethylene oxide are added to each alcohol, [7] however ethoxylated alcohols can be more prone to ethoxylation than the starting alcohol, making the reaction difficult to control and leading to the formation of a product with varying repeat unit length (the value of n in the equation above).