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2,4-Dinitrophenol (2,4-DNP or simply DNP) is an organic compound with the formula HOC 6 H 3 (NO 2) 2. It has been used in explosives manufacturing and as a pesticide and herbicide. In humans, DNP causes dose-dependent mitochondrial uncoupling , causing the rapid loss of ATP as heat and leading to uncontrolled hyperthermia —up to 44 °C (111 ...
2,4-Dinitrophenol (DNP) is a very strong thermogenic drug used for fat loss which produces a dose-dependent increase in body temperature, to the point where it can induce death by hyperthermia. It works as a mitochondrial oxidative phosphorylation uncoupler, disrupting the mitochondrial electron transport chain .
HU6 is a prodrug of the mitochondrial uncoupler 2,4-dinitrophenol (DNP) that is intended to "minimize the rapid absorption and high peak blood concentrations of DNP to provide a wider therapeutic index and improve safety."
Apotex Inc. is a Canadian pharmaceutical corporation. [4] Founded in 1974 by Barry Sherman, the company is the largest producer of generic drugs in Canada, with annual sales exceeding CA$2.5 billion. [5]
Rexall was founded in 1904 during the early days of the United Drug Company and quickly established itself as a major retail pharmacy chain. At the same time, Tamblyn Drugs was establishing itself in Toronto, Ontario, and would eventually become Pharma Plus. These two companies would later merge to form the Rexall Pharmacy Group.
The substance has killed at least 33 people in the UK. For premium support please call: 800-290-4726 more ways to reach us
Over the past year, a number of high-profile companies have done about-faces on diversity, including Meta (), Walmart (), McDonald's (), Lowe’s (), Ford (), Tractor Supply (), and John Deere ...
Overdose caused fatal hyperthermia and DNP also caused cataracts in some users. After the passage of the Food, Drug, and Cosmetic Act in 1938, the FDA banned DNP for human consumption. [37] Amphetamines (marketed as Benzedrine) became popular for weight loss during the late 1930s. They worked primarily by suppressing appetite, and had other ...