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Neurodegeneration with brain iron accumulation is a heterogenous group of inherited neurodegenerative diseases, still under research, in which iron accumulates in the basal ganglia, either resulting in progressive dystonia, parkinsonism, spasticity, optic atrophy, retinal degeneration, neuropsychiatric, or diverse neurologic abnormalities. [1]
Neuroferritinopathy was originally described with hallmark features of neurodegeneration and iron accumulation in the brain, leading it to be classified with other neurodegeneration with brain iron accumulation (NBIA) disorders which share similar symptoms and imaging findings. Over time single-gene causes have been found for many NBIA ...
[55] [63] Iron can be found in three forms in the brain – magnetite, hemoglobin (blood) and ferritin (protein), and areas of the brain related to motor function generally contain more iron. [63] [64] Magnetite can be found in the hippocampus. The hippocampus is associated with information processing, specifically learning and memory. [63]
Iron is a mineral that is crucial for optimal health and well-being. Found naturally in many foods and dietary supplements, it is a key component of hemoglobin, the part of red blood cells ...
The red nucleus is pale pink, which is believed to be due to the presence of iron in at least two different forms: hemoglobin and ferritin. [2] The structure is located in the midbrain tegmentum next to the substantia nigra and comprises caudal magnocellular and rostral parvocellular components. [1]
There’s one slight problem: While iron deficiency was found to be “very common” in the “apparently healthy” general population and associated with all-cause mortality in a 2020 article ...
Superficial hemosiderosis of the central nervous system is a disease of the brain resulting from chronic iron deposition in neuronal tissues associated with cerebrospinal fluid. This occurs via the deposition of hemosiderin in neuronal tissue, and is associated with neuronal loss, gliosis , and demyelination of neuronal cells.
A 24-year-old woman in China was found to be completely without a cerebellum. Beneath the brain's two hemispheres rests the cerebellum, a small but powerful mass of tissue that houses about 50 ...