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Henrietta Lacks (born Loretta Pleasant; August 1, 1920 – October 4, 1951) [2] was an African-American woman [5] whose cancer cells are the source of the HeLa cell line, the first immortalized human cell line [B] and one of the most important cell lines in medical research. An immortalized cell line reproduces indefinitely under specific ...
SK-OV-3 (also known as SKOV-3; SK.OV.3; SKOV3; Skov3 and SKO3) is an ovarian cancer cell line derived from the ascites of a 64-year-old Caucasian female with an ovarian serous cystadenocarcinoma. [1] The SK-OV-3 cell line is also hypodiploid, with a modal number of chromosomes of 43 (range 42-45), occurring in 63.3% of cells.
In 2020, Cancer Cell made a number of changes to increase diversity and inclusion of underrepresented minorities in cancer research and oncology. In June 2020, the journal announced the new members of its advisory board (previously editorial board), which includes a higher representation of female scientists (>40%) and physicians (~50%) and ...
Richard B. Gaynor is an American physician specializing in hematology-oncology, educator, drug developer, and business executive.He served as an Associate Professor of Medicine at UCLA School of Medicine (Los Angeles, CA) for nearly a decade, and subsequently as an endowed Professor of Medicine and Microbiology at the University of Texas Southwestern Medical School prior to joining the ...
n/a Ensembl ENSG00000181143 n/a UniProt Q8WXI7 n/a RefSeq (mRNA) NM_024690 NM_001401501 n/a RefSeq (protein) NP_078966 n/a Location (UCSC) Chr 19: 8.85 – 8.98 Mb n/a PubMed search n/a Wikidata View/Edit Human Mucin-16 (MUC-16) also known as Ovarian cancer-related tumor marker CA125 is a protein that in humans is encoded by the MUC16 gene. MUC-16 is a member of the mucin family glycoproteins ...
According to research, most ovarian cancers start at the epithelial layer which is the lining of the ovary. Within this epithelial group ovarian clear-cell carcinoma makes up 5–10%. It was recognized as a separate category of ovarian cancer by the World Health Organization in 1973. Its incidence rate differs across various ethnic groups.
For certain cancers, people born in 1990 face two-to-three times the risks that those born in 1955 did, according to the research published in the journal Lancet Public Health.
Serous ovarian cancer is the most common type of epithelial ovarian cancer and it accounts for about two-thirds of cases of epithelial ovarian cancer. [28] Low-grade serous carcinoma is less aggressive than high-grade serous carcinomas, though it does not typically respond well to chemotherapy or hormonal treatments. [ 28 ]