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  2. Transplant rejection - Wikipedia

    en.wikipedia.org/wiki/Transplant_rejection

    Acute rejection is a category of rejection that occurs on the timescale of weeks to months, with most episodes occurring within the first 3 months to 1 year after transplantation. [ 6 ] [ 8 ] Unlike hyperacute rejection, acute rejection is thought to arise from two distinct immunological mechanisms as lymphocytes , a subset of white blood cells ...

  3. Hematopoietic stem cell transplantation - Wikipedia

    en.wikipedia.org/wiki/Hematopoietic_stem_cell...

    Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood, in order to replicate inside a patient and produce additional normal blood cells.

  4. Adding stem cells to a kidney transplant could get patients ...

    www.aol.com/news/adding-stem-cells-kidney...

    A novel approach to organ transplantation allowed patients to wean off anti-rejection drugs after two years, according to the results of a phase 3 clinical trial presented Monday.

  5. Stem-cell therapy - Wikipedia

    en.wikipedia.org/wiki/Stem-cell_therapy

    Stem-cell therapy uses stem cells to treat or prevent a disease or condition. [1] As of 2024, the only FDA-approved therapy using stem cells is hematopoietic stem cell transplantation. [2] [3] This usually takes the form of a bone marrow or peripheral blood stem cell transplantation, but the cells can also be derived from umbilical cord blood.

  6. Tissue transplantation - Wikipedia

    en.wikipedia.org/wiki/Tissue_transplantation

    This field could revolutionize tissue transplants by synthesizing personalized grafts for enhanced integration without immune rejection and reducing reliance on donors. [33] A diagram of stem cell differentiation, showing the potential of stem cells in creating personalised tissues of various body parts for transplantation.

  7. A 7th person with HIV is probably cured after stem cell ... - AOL

    www.aol.com/news/7th-person-hiv-probably-cured...

    Edmonds, the oldest potential cure case at 63 when he received a stem-cell transplant for AML in 2019, received reduced-intensity chemotherapy because of his age. Off antiretrovirals since March ...

  8. Graft-versus-host disease - Wikipedia

    en.wikipedia.org/wiki/Graft-versus-host_disease

    Prochymal is the first stem cell drug to be approved for a systemic disease. [50] In January 2016, Mesoblast released results of a phase 2 clinical trial on 241 children with acute Graft-versus-host disease, that was not responsive to steroids. [51] The trial was of a mesenchymal stem cell therapy known as remestemcel-L or MSC-100-IV. Survival ...

  9. Alloantigen recognition - Wikipedia

    en.wikipedia.org/wiki/Alloantigen_recognition

    Rejection mediated by T lymphocytes sensitized by direct allorecognition pathway is predominant in the short period after the transplantation, but usually subsides with depletion of passenger cells while indirect recognition contributes to continuing graft damage and plays role in chronic rejection.