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In parallel to albuminuria in 1936, discussion on renal lesions observed in patients with diabetes led to the description, by Kimmelstiel and Wilson, of the characteristic nodular fibrotic observed in the diabetic glomeruli (Kimmelstiel and Wilson, 1936b). Kimmelstiel and Wilson introduced the term diabetic nephropathy (DN) to define a clinical ...
Bizarre parosteal osteochondromatous proliferation (BPOP), also known as Nora's lesion, [4] is a type of non-cancerous bone tumor belonging to the group of cartilage tumors. [ 1 ] [ 2 ] [ 5 ] It is generally seen in the tubular bones of the hands and feet , [ 6 ] where it presents with a rapidly enlarging painless lump in a finger or toe.
Other symptoms include tiredness, headaches, a general feeling of illness, nausea, vomiting, frequent daytime urination, lack of appetite, itchy skin, and leg swelling. [2] The clinical presentation of diabetic nephropathy (DN) is characterized by proteinuria (protein in the urine), hypertension and progressive loss of kidney function.
[19] [20] Clinically, the diagnosis of any particular skin condition is made by gathering pertinent information regarding the presenting skin lesion(s), including the location (such as arms, head, legs), symptoms (pruritus, pain), duration (acute or chronic), arrangement (solitary, generalized, annular, linear), morphology (macules, papules ...
A hand imitating an ulnar claw. The metacarpophalangeal joints of the 4th and 5th fingers are extended and the Interphalangeal joints of the same fingers are flexed.. An ulnar claw, also known as claw hand or Spinster’s Claw, is a deformity or an abnormal attitude of the hand that develops due to ulnar nerve damage causing paralysis of the lumbricals.
[1] [5] Currently, symptomatic treatments are NSAIDs and steroids or surgical procedures. [5] [6] In 1868, PDP was first described by Friedreich as 'excessive growth of bone of the entire skeleton'. Touraine, Solente and Golé described PDP as the primary form of bone disease hypertrophic osteoarthropathy in 1935 and distinguished its three ...
If lesions affecting the branches of the ulnar nerve that run to the wasted muscles are excluded, the lesion is almost sure to be located in the anterior horn of the spinal cord at the C8-T1 level. [2] It has been proposed as a relatively specific sign for amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease).
Keratolysis exfoliativa (also known as"lamellar dyshidrosis", [1] "recurrent focal palmar peeling", [2] "recurrent palmar peeling" [1]: 212 [2]) is a sometimes harmless, sometimes painful skin condition that can affect the focal surface of the fingers and/or the palm or soles of the feet.