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This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.
Alpidem (Ananxyl) 1995. Worldwide. Not approved in the US, withdrawn in France in 1994 [ 4 ] and the rest of the market in 1995 because of rare but serious hepatotoxicity. [ 3 ][ 5 ] Alosetron (Lotronex) 2000. US. Serious gastrointestinal adverse events; ischemic colitis; severe constipation. [ 2 ] Reintroduced 2002 with restricted indication ...
good. Frequency. 0.2% for those on biphosphonate type drugs >4 years. Medication-related osteonecrosis of the jaw (MON, MRONJ) is progressive death of the jawbone in a person exposed to a medication known to increase the risk of disease, in the absence of a previous radiation treatment.
Gemtuzumab ozogamicin. Gemtuzumab ozogamicin, sold under the brand name Mylotarg®, is an antibody-drug conjugate (a drug-linked monoclonal antibody) that is used to treat acute myeloid leukemia (AML). [6][8][9] The most common side effects include infection, febrile neutropenia, decreased appetite, hyperglycemia, mucositis, hypoxia, hemorrhage ...
The first list was published in 1977 and included 208 medications. [8] [2] [9] The WHO updates the list every two years. [10] There are 306 medications in the 14th list in 2005, [11] 410 in the 19th list in 2015, [10] 433 in the 20th list in 2017, [12] [13] 460 in the 21st list in 2019, [14] [15] [16] and 479 in the 22nd list in 2021.
OLED. An organic light-emitting diode (OLED), also known as organic electroluminescent (organic EL) diode, [ 1 ][ 2 ] is a type of light-emitting diode (LED) in which the emissive electroluminescent layer is an organic compound film that emits light in response to an electric current. This organic layer is situated between two electrodes ...
Lecanemab, sold under the brand name Leqembi, is a monoclonal antibody medication used for the treatment of Alzheimer's disease. [ 3 ][ 4 ] Lecanemab is an amyloid beta -directed antibody. [ 3 ] It is given via intravenous infusion to patients with mild cognitive impairment or mild dementia. [ 3 ] In clinical trials, it demonstrated modest ...
Contents. Nintedanib. Nintedanib, sold under the brand names Ofev and Vargatef, is an oral medication used for the treatment of idiopathic pulmonary fibrosis and along with other medications for some types of non-small-cell lung cancer. [ 5 ] In March 2020, it was approved for use in the United States to treat chronic fibrosing (scarring ...