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Pocapavir (V-073, SCH48973) is an antiviral drug which acts as a capsid inhibitor. It was developed for the treatment of enterovirus infections, including diseases such as polio and coxsackievirus , and also has activity against parechoviruses .
The results of two randomized, double blind, placebo studies found Pleconaril treatment could benefit patients with colds due to picornaviruses. [14] Participants in the studies were healthy adults from Canada and the United States, with self-diagnosed colds that had occurred within 24 hours of trial enrollment.
Enterovirus B includes coxsackievirus B1,2,3,4,5,6; coxsackievirus A9; echovirus 1–33 and enterovirus B69–113. [11] Coxsackie B viruses are found worldwide and can cause myocarditis (inflammation of the heart); pericarditis (inflammation of the sac surrounding the heart); meningitis (inflammation of the membranes that line the brain and ...
Hand, foot, and mouth disease (HFMD) is a common infection caused by a group of enteroviruses. [10] It typically begins with a fever and feeling generally unwell. [10] This is followed a day or two later by flat discolored spots or bumps that may blister, on the hands, feet and mouth and occasionally buttocks and groin.
Enterovirus D68 (EV-D68) is a member of the Picornaviridae family, an enterovirus. First isolated in California in 1962 and once considered rare, it has been on a worldwide upswing in the 21st century.
Echovirus is a polyphyletic group of viruses associated with enteric disease in humans. The name is derived from "enteric cytopathic human orphan virus".These viruses were originally not associated with disease, but many have since been identified as disease-causing agents.
The primary treatment of gastroenteritis in both children and adults is rehydration. This is preferably achieved by drinking rehydration solution, although intravenous delivery may be required if there is a decreased level of consciousness or if dehydration is severe.
Enterovirus 71 (EV71), also known as Enterovirus A71 (EV-A71), is a virus of the genus Enterovirus in the Picornaviridae family, [1] notable for its role in causing epidemics of severe neurological disease and hand, foot, and mouth disease in children. [2] It was first isolated and characterized from cases of neurological disease in California ...