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Ibuprofen is practically insoluble in water, but very soluble in most organic solvents like ethanol (66.18 g/100 mL at 40 °C for 90% EtOH), methanol, acetone and dichloromethane. [62] The original synthesis of ibuprofen by the Boots Group started with the compound isobutylbenzene. The synthesis took six steps.
It decays according to its 21.772-year half-life emitting mostly beta (98.62%) and some alpha particles (1.38%); [38] the successive decay products are part of the actinium series. Owing to the low available amounts, low energy of its beta particles (maximum 44.8 keV) and low intensity of alpha radiation, 227