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Neisseria meningitidis, often referred to as the meningococcus, is a Gram-negative bacterium that can cause meningitis and other forms of meningococcal disease such as meningococcemia, a life-threatening sepsis. The bacterium is referred to as a coccus because it is round, and more specifically a diplococcus because of its tendency to form ...
Neisseria is a large genus of bacteria that colonize the mucosal surfaces of many animals. Of the 11 species that colonize humans, only two are pathogens, N. meningitidis and N. gonorrhoeae. Neisseria species are Gram-negative bacteria included among the Pseudomonadota, a large group of Gram-negative forms. Neisseria diplococci resemble coffee ...
NmVac4-A/C/Y/W-135 is the commercial name of the polysaccharide vaccine against the bacterium (specifically serogroups A, C, Y, and W-135) that causes meningococcal meningitis. The product, by JN-International Medical Corporation, is designed and formulated to be used in developing countries for protecting populations during meningitis disease ...
10–20% mortality generally. 10% mortality with treatment. Meningococcal disease describes infections caused by the bacterium Neisseria meningitidis (also termed meningococcus). [1] It has a high mortality rate if untreated but is vaccine-preventable. [2] While best known as a cause of meningitis, it can also result in sepsis, which is an even ...
Bacterial meningitis, although rare, is an infection that can turn lethal, say experts. (Getty Images) (Getty Images) Three teachers in Colorado's Cherry Creek school district suddenly died last ...
N-acetylneuraminic acid synthase dimer, Neisseria meningitidis. Identifiers; EC no. 2.5.1.56: CAS no. 37290-66-7 ... only one structure has been solved for this class ...
In the case of Neisseria meningitidis, the lipid A portion of the molecule has a symmetrical structure and the inner core is composed of 3-deoxy-D-manno-2-octulosonic acid (KDO) and heptose (Hep) moieties. The outer core oligosaccharide chain varies depending on the bacterial strain. [7] [22]
Outer membrane adhesin OpcA protein family consists of several Neisseria species specific outer membrane proteins. Neisseria meningitidis causes meningococcal meningitis and sepsis. Opc (formerly called 5C) is one of the major outer membrane proteins and has been shown to play an important role in meningococcal adhesion and invasion of ...