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  2. Addiction vulnerability - Wikipedia

    en.wikipedia.org/wiki/Addiction_vulnerability

    Many factors have been identified as being associated with increased risk of substance use during this period of development including individual differences (e.g., negative affect, decreased harm avoidance, and low motivation for achievement), biological (e.g., genetic predisposition and neurological development), and environmental factors (e ...

  3. Alcohol-related brain damage - Wikipedia

    en.wikipedia.org/wiki/Alcohol-related_brain_damage

    High impulsivity has [also] been found in families with alcoholism, suggestive of a genetic link. Thus, the genetics of impulsivity overlaps with genetic risks for alcohol use disorder and possibly alcohol neurodegeneration". [7] There is also a genetic risk for proinflammatory cytokine mediated alcohol-related brain damage. There is evidence ...

  4. Alcoholism - Wikipedia

    en.wikipedia.org/wiki/Alcoholism

    The concept of "harmful use" (as opposed to "abuse") was introduced in 1992's ICD-10 to minimize underreporting of damage in the absence of dependence. [116] The term "alcoholism" was removed from ICD between ICD-8/ICDA-8 and ICD-9. [120] ICD-11: Episode of harmful use of alcohol, Harmful pattern of use of alcohol, or Alcohol dependence

  5. Disease model of addiction - Wikipedia

    en.wikipedia.org/wiki/Disease_model_of_addiction

    The disease model of addiction describes an addiction as a disease with genetic, biological, neurological or environmental origin. [1] The traditional medical model of disease requires only an abnormal condition causing distress, discomfort or dysfunction to an affected individual.

  6. Substance abuse - Wikipedia

    en.wikipedia.org/wiki/Substance_abuse

    Substance abuse can be a factor that affects the physical and mental health of veterans. Substance abuse may also harm personal and familial relationships, leading to financial difficulty. There is evidence to suggest that substance abuse disproportionately affects the homeless veteran population. A 2015 Florida study, which compared causes of ...

  7. Causes of mental disorders - Wikipedia

    en.wikipedia.org/wiki/Causes_of_mental_disorders

    Risk factors for mental illness include psychological trauma, adverse childhood experiences, genetic predisposition, and personality traits. [7] [8] Correlations between mental disorders and substance use are also found to have a two way relationship, in that substance use can lead to the development of mental disorders and having mental disorders can lead to substance use/abuse.

  8. Addiction - Wikipedia

    en.wikipedia.org/wiki/Addiction

    Drug addiction, which belongs to the class of substance-related disorders, is a chronic and relapsing brain disorder that features drug seeking and drug abuse, despite their harmful effects. [31] This form of addiction changes brain circuitry such that the brain's reward system is compromised, [ 32 ] causing functional consequences for stress ...

  9. Substance dependence - Wikipedia

    en.wikipedia.org/wiki/Substance_dependence

    Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption ...