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Epidemic typhus, also known as louse-borne typhus, is a form of typhus so named because the disease often causes epidemics following wars and natural disasters where civil life is disrupted. [ 4 ] [ 5 ] Epidemic typhus is spread to people through contact with infected body lice , in contrast to endemic typhus which is usually transmitted by fleas .
Typhus, also known as typhus fever, is a group of infectious diseases that include epidemic typhus, scrub typhus, and murine typhus. [1] Common symptoms include fever, headache, and a rash. [1] Typically these begin one to two weeks after exposure. [2] The diseases are caused by specific types of bacterial infection. [1]
Scrub typhus or bush typhus is a form of typhus caused by the intracellular parasite Orientia tsutsugamushi, a Gram-negative α-proteobacterium of family Rickettsiaceae first isolated and identified in 1930 in Japan. [2] [3]
Rickettsia typhi is a causative agent of murine typhus (endemic typhus) in humans and is distributed worldwide. [26] It is an acute, febrile illness that is mainly transmitted by the fleas of rodents, commonly associated with cities and ports where urban rats ( Rattus rattus and Rattus norvegicus ) are abundant. [ 26 ]
Brill–Zinsser disease is a delayed relapse of epidemic typhus, caused by Rickettsia prowazekii.After a patient contracts epidemic typhus from the fecal matter of an infected louse (Pediculus humanus), the rickettsia can remain latent and reactivate months or years later, with symptoms similar to or even identical to the original attack of typhus, including a maculopapular rash.
Los Angeles County is warning its residents to look out for fleas that could be carrying typhus after more than 40 cases have been reported in the area.
Prof. Rudolf Weigl's anti-typhus vaccine at POLIN Museum of the History of Polish Jews in Warsaw. In 1930, following Charles Nicolle's 1909 discovery that lice were the vector of epidemic typhus, and following the work done on a vaccine for the closely related Rocky Mountain spotted fever, Weigl took the next step and developed a technique to produce a typhus vaccine by growing infected lice ...
The same symptoms seen in patients with epidemic typhus are seen in patients with Brill's Disease, only in less severe form. [6] Brill's Disease can affect patients for the entirety of their lives, with cases being documented after more than forty years of contracting epidemic typhus.