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These are located on top of the taste receptor cells that constitute the taste buds. The taste receptor cells send information detected by clusters of various receptors and ion channels to the gustatory areas of the brain via the seventh, ninth and tenth cranial nerves. On average, the human tongue has 2,000–8,000 taste buds. [2]
The sense of taste is based on the detection of chemicals by specialized taste cells in the mouth. The mouth, throat, larynx, and esophagus all have taste buds, which are replaced every ten days. Each taste bud contains receptor cells. [21] Afferent nerves make contact with the receptor cells at the base of the taste bud. [23]
Although these cells communicate directly with the brain, the virus does not exhibit strong infection of other nerve cells in the central nervous system. Many of the neurological sequelae appear to result from damage to the vascular cells of the brain or from damage resulting from hypoxia (i.e., limitations in the oxygen supply for the brain).
Many who have suffered through COVID-19 find themselves unable to taste or smell. Sometimes, their senses are distorted, with certain foods tasting metallic or others smelling rancid to them.
Taste cells synapse with primary sensory axons that run in the chorda tympani and greater superficial petrosal branches of the facial nerve (cranial nerve VII), the lingual branch of the glossopharyngeal nerve (cranial nerve IX), and the superior laryngeal branch of the vagus nerve (Cranial nerve X) to innervate the taste buds in the tongue ...
There may be another addition to the growing list of strange possible symptoms of the new coronavirus: “Covid tongue.”. A British researcher who is helping to track Covid-19 warning signs is ...
COVID-19-related ansomnia is, for the most part, believed to be temporary. "Current reports have indicated as few as three to five days, up to several weeks after recovery for those patients who ...
As a result, emerging research indicates that the various variants of COVID-19 might be associated with differences in the severity of ageusia experienced by patients, as well as the severity of other taste and smell disorders. Implying that certain strains of the virus may have differing impacts on the sensory functions of affected individuals.