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Autoimmune gastrointestinal dysmotility (AGID) is an autoimmune disease autonomic neuropathy affecting the gastrointestinal organs and digestive system of the body. Dysmotility is when the strength or coordination of the esophagus , stomach or intestines muscles do not work as they should.
Abnormal motility Studies have shown altered muscle contractility and tone, bowel compliance, and transit may contribute to many of the gastrointestinal symptoms of FGID which may include diarrhea, constipation, and vomiting. [20] Visceral hypersensitivity In FGID there is poor association of pain with GI motility in many functional GI disorders.
Gastrointestinal motility disorders occur when the digestive tract, especially its muscles or nerves, malfunctions. They are sometimes treated by physicians with subspecialty training in neurogastroenterology.
Motility disorders are the second classification of gastrointestinal disorder studied by neurogastroenterologists. Motility disorders are divided by what they affect, with four regions: The esophagus, the stomach, the small intestines, and the large intestines.
The enteric nervous system directly controls the gut motility, whereas the extrinsic nerve pathways influence gut contractility indirectly through modifying this enteric innervation. [3] In almost all cases of neurogenic bowel dysfunction it is the extrinsic nervous supply affected and the enteric nervous supply remains intact.
Gastrointestinal diseases (abbrev. GI diseases or GI illnesses) refer to diseases involving the gastrointestinal tract, namely the esophagus, stomach, small intestine, large intestine and rectum; and the accessory organs of digestion, the liver, gallbladder, and pancreas. Deaths due to digestive diseases per million persons in 2012
Small intestinal bacterial overgrowth (SIBO), also termed bacterial overgrowth, or small bowel bacterial overgrowth syndrome (SBBOS), is a disorder of excessive bacterial growth in the small intestine. Unlike the colon (or large bowel), which is rich with bacteria, the small bowel usually has fewer than 100,000 organisms per millilitre. [1]
Autoimmune conditions — conditions including systemic lupus erythematosus and scleroderma lead to collagen vascular deposition [22] and gastrointestinal motility disruption; Mitochondrial disease [23] - IPO is a known presentation for mitochondrial disease; Endocrine disorders [4] Certain medications. [15]
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