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Croup (/ k r uː p / KROOP), also known as croupy cough, is a type of respiratory infection that is usually caused by a virus. [2] The infection leads to swelling inside the trachea, which interferes with normal breathing and produces the classic symptoms of "barking/brassy" cough, inspiratory stridor and a hoarse voice. [2]
The Enzyme Commission refers to this family as SARS coronavirus main proteinase (M pro; EC 3.4.22.69). The 3CL protease corresponds to coronavirus nonstructural protein 5 (nsp5). The "3C" in the common name refers to the 3C protease (3C pro ) which is a homologous protease found in picornaviruses .
This registry based, multi-center, multi-country data provide provisional support for the use of ECMO for COVID-19 associated acute hypoxemic respiratory failure. Given that this is a complex technology that can be resource intense, guidelines exist for the use of ECMO during the COVID-19 pandemic. [85] [86] [87]
A World Health Organization infographic that states that hydroxychloroquine does not prevent illness or death from COVID-19. Chloroquine and hydroxychloroquine are anti-malarial medications also used against some auto-immune diseases. [1] Chloroquine, along with hydroxychloroquine, was an early experimental treatment for COVID-19. [2]
Porcine coronavirus HKU15 (PorCov‑HKU15) 2014 Discovered in Hong Kong, China. [37] Humans Coronavirus disease 2019 (COVID‑19) Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), a strain of SARSr‑CoV: 2019 Discovered in Wuhan, China. [38] [39] Caused the COVID-19 pandemic. Possibly originated from pangolins, horseshoe bats ...
Longer-term effects of COVID-19 have become a prevalent aspect of the disease itself. These symptoms can be referred to by many names including post-COVID-19 syndrome, long COVID, and long haulers syndrome. An overall definition of post-COVID conditions (PCC) can be described as a range of symptoms that can last for weeks or months. [83]
In July 2020, the European Medicines Agency (EMA) started reviewing results from the RECOVERY study arm that involved the use of dexamethasone in the treatment of patients with COVID-19 admitted to the hospital to provide an opinion on the results. It focused particularly on the potential use of the drug for the treatment of adults with COVID-19.
Human coronavirus OC43 [1] (HCoV-OC43) is a member of the species Betacoronavirus 1, which infects humans and cattle. [ 2 ] [ 3 ] The infecting coronavirus is an enveloped , positive-sense , single-stranded RNA virus that enters its host cell by binding to the N-acetyl-9-O-acetylneuraminic acid receptor . [ 4 ]