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Quinine is a basic amine and is usually provided as a salt. Various existing preparations include the hydrochloride, dihydrochloride, sulfate, bisulfate and gluconate. In the United States, quinine sulfate is commercially available in 324 mg tablets under the brand name Qualaquin.
Herapathite, or iodoquinine sulfate, is a chemical compound whose crystals are dichroic and thus can be used for polarizing light. It was discovered in 1852 [1] by William Bird Herapath, a Bristol surgeon and chemist. One of his pupils found that adding iodine to the urine of a dog that had been fed quinine produced unusual green
As with other quinoline antimalarial drugs, the antimalarial mechanism of action of quinine has not been fully resolved. The most accepted model is based on hydrochloroquinine and involves the inhibition of hemozoin biocrystallization, which facilitates the aggregation of cytotoxic heme. Free cytotoxic heme accumulates in the parasites, causing ...
People who rely on Qualaquin, also known as quinine sulfate, to combat their nighttime leg cramps are putting their lives at risk, warned the Food and Drug Administration. The federal agency ...
Skraup synthesis using ferrous sulfate, glycerol, aniline, nitrobenzene, and sulfuric acid. A number of other processes exist, which require specifically substituted anilines or related compounds: Camps quinoline synthesis using an o-acylaminoacetophenone and hydroxide; Friedländer synthesis using 2-aminobenzaldehyde and acetaldehyde
Hypersensitivity to quinine, mefloquine, quinidine, or dextromethorphan/quinidine with a history of thrombocytopenia, hepatitis, bone marrow depression or lupus-like syndrome induced by these drugs; QT interval, prolonged or congenital long QT syndrome or a history suggesting torsades de pointes
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Hydroquinone, also known as benzene-1,4-diol or quinol, is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical formula C 6 H 4 (OH) 2.