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In analytical chemistry, the detection limit, lower limit of detection, also termed LOD for limit of detection or analytical sensitivity (not to be confused with statistical sensitivity), is the lowest quantity of a substance that can be distinguished from the absence of that substance (a blank value) with a stated confidence level (generally 99%).
A calibration curve plot showing limit of detection (LOD), limit of quantification (LOQ), dynamic range, and limit of linearity (LOL).. In analytical chemistry, a calibration curve, also known as a standard curve, is a general method for determining the concentration of a substance in an unknown sample by comparing the unknown to a set of standard samples of known concentration. [1]
There are different definitions within laboratory quality control, wherein "analytical sensitivity" is defined as the smallest amount of substance in a sample that can accurately be measured by an assay (synonymously to detection limit), and "analytical specificity" is defined as the ability of an assay to measure one particular organism or ...
The domain of f and g can be any set for which the limit is defined: e.g. real numbers, complex numbers, positive integers. The same notation is also used for other ways of passing to a limit: e.g. x → 0, x ↓ 0, | x | → 0. The way of passing to the limit is often not stated explicitly, if it is clear from the context.
For example, the ML estimator from the previous example may be attained as the limit of Bayes estimators with respect to a uniform prior, [,] with increasing support and also with respect to a zero-mean normal prior (,) with increasing variance. So neither the resulting ML estimator is unique minimax nor the least favorable prior is unique.
The Bekenstein bound limits the amount of information that can be stored within a spherical volume to the entropy of a black hole with the same surface area. Thermodynamics limit the data storage of a system based on its energy, number of particles and particle modes. In practice, it is a stronger bound than the Bekenstein bound.
A minimum detectable signal is a signal at the input of a system whose power allows it to be detected over the background electronic noise of the detector system. It can alternately be defined as a signal that produces a signal-to-noise ratio of a given value m at the output.
where denotes the limit superior (possibly ; if the limit exists it is the same value). If r < 1, then the series converges absolutely. If r > 1, then the series diverges. If r = 1, the root test is inconclusive, and the series may converge or diverge.