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Bordetella pertussis is a Gram-negative, aerobic, pathogenic, encapsulated coccobacillus bacterium of the genus Bordetella, and the causative agent of pertussis or whooping cough. Its virulence factors include pertussis toxin , adenylate cyclase toxin , filamentous haemagglutinin , pertactin , fimbria , and tracheal cytotoxin .
Whooping cough (/ ˈ h uː p ɪ ŋ / or / ˈ w uː p ɪ ŋ /), also known as pertussis or the 100-day cough, is a highly contagious, vaccine-preventable bacterial disease. [1] [10] Initial symptoms are usually similar to those of the common cold with a runny nose, fever, and mild cough, but these are followed by two or three months of severe coughing fits. [1]
Due to the fact B. pertussis is only found in humans and shows little genetic variation from the other Bordetella species, it is thought that it was derived from a common ancestor in recent years. B. parapertussis can affect both humans and other mammals, primarily sheep. Similar to B. pertussis, it causes whooping cough in babies. Yet, when ...
What is whooping cough? Whooping cough is a highly contagious bacterial infection that affects children and adults alike - though it's more common and concerning in infants and toddlers. The ...
What is whooping cough? According to the Centers for Disease Control. whooping cough, also known as pertussis, is a highly contagious respiratory illness caused by the bacteria Bordetella pertussis.
Two of the most overlooked symptoms of whooping cough are a runny nose and congestion. That's one of the things that makes it so tricky to catch early. "Symptoms may mirror that of the common cold.
Adenylate cyclase toxin from Bordetella pertussis is a 1706 amino acid residue long protein.The protein consists of three domains: from the N-terminus up to roughly residue 400, there is an adenylate-cyclase domain; between residues 500 and 700, there is a hydrophobic domain; and from residue 1000 to the C-terminus, there are calcium binding repeats.
“Symptoms also may not be as bad at night,” Dr. Coleman says. But if you’ve been dealing with a cough for a while, or if it feels like your cough is getting worse, he says it’s time to see ...