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When a dog has wild-type alleles at all three genes, it will have a yellow coat. When the dog has a loss-of-function allele at MC1R, it will have a yellow coat regardless of the genes it carries on the other two genes. Only a dominant black allele at CBD103 will produce a black coat color in dogs possessing wild-type alleles at MC1R and Agouti. [8]
To understand why a dog's coat looks the way it does based on its genes requires an understanding of a handful of genes and their alleles which affect the dog's coat. For example, to find how a black and white greyhound that seems to have wavy hair got its coat, the dominant black gene with its K and k alleles, the (white) spotting gene with ...
A Labrador exhibiting a yellow coat colour. Domestic dogs exhibit diverse coat colours and patterns.In many mammals, different colour patterns are the result of the regulation of the Agouti gene, which can cause hair follicles to switch from making black or brown pigments to yellow or nearly white pigments.
If a dog carries wild type alleles at all three loci, the dog will have a yellow coat. If a dog has a loss-of-function mutation at MC1R, it will also have a yellow coat, regardless of the genotypes at the other two loci. Dogs carrying wild-type alleles for MC1R and Agouti, together with the black allele of CBD103, will have a black coat. [17] [a]
The breed typically weighs between 45 and 100 pounds (20 and 45 kg), [9] [10] with the breed standard allowing for significantly lighter animals than is typical, stating a minimum 40 pounds (18 kg) for mature male dogs and 35 pounds (16 kg) for mature female dogs. [3] The Black Mouth Cur has a short, dense coat that is typically yellow, fawn or ...
An agouti dog, also called wolf sable. In dogs, the agouti gene is associated with various coat colors and patterns. [10]The alleles at the A locus are related to the production of agouti-signaling protein (ASIP) and determine whether an animal expresses an agouti appearance and, by controlling the distribution of pigment in individual hairs, what type of agouti.
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